• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

表现为双侧下睑内侧外翻的小淋巴细胞淋巴瘤。

Small lymphocytic lymphoma presenting as bilateral medial lower eyelid ectropion.

作者信息

Anchouche Sonia, Chang Kenneth, Yao Christopher Mkl, Hojilla Carlo, Nijhawan Navdeep, Nassrallah Georges

机构信息

Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada.

Department of Otolaryngology Head and Neck Surgery, University of Toronto, Toronto, Ontario, Canada.

出版信息

Am J Ophthalmol Case Rep. 2025 May 9;39:102352. doi: 10.1016/j.ajoc.2025.102352. eCollection 2025 Sep.

DOI:10.1016/j.ajoc.2025.102352
PMID:40496937
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12149541/
Abstract

PURPOSE

Herein, we present a case of new-onset medial ectropion of the lower eyelids and persistent painless cervical lymphadenopathy in an 85-year-old man highlighting a unique presentation of small lymphocytic lymphoma (SLL).

OBSERVATIONS

Physical examination revealed bilateral medial ectropion with associated follicular changes to the palpebral conjunctiva and extensive cervical lymphadenopathy. Conjunctival biopsies were taken during ectropion repair in addition to fine needle biopsy of the cervical lymphadenopathy which both independently confirmed a diagnosis of SLL. Surgical intervention, including bilateral lateral tarsal strip and medial spindle procedures, yielded excellent postoperative outcomes. Given the patient's staging, he remained under observation until treatment was warranted to address progressive lymphadenopathy.

CONCLUSIONS AND IMPORTANCE

This report contributes valuable new insight into the ocular manifestations of lymphoproliferative disease.

摘要

目的

在此,我们报告一例85岁男性新发下睑内侧外翻和持续性无痛性颈部淋巴结病的病例,突出了小淋巴细胞淋巴瘤(SLL)的一种独特表现。

观察结果

体格检查发现双侧内侧外翻,睑结膜伴有滤泡样改变,以及广泛的颈部淋巴结病。除了对颈部淋巴结病进行细针穿刺活检外,还在睑外翻修复过程中进行了结膜活检,两者均独立确诊为SLL。手术干预,包括双侧外侧睑板条和内侧纺锤形手术,术后效果极佳。鉴于患者的分期,在有必要治疗进行性淋巴结病之前,他一直处于观察状态。

结论与意义

本报告为淋巴增殖性疾病的眼部表现提供了有价值的新见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17c5/12149541/fe6a9f53813d/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17c5/12149541/109d7719e323/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17c5/12149541/d5f6cd6d3614/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17c5/12149541/fe6a9f53813d/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17c5/12149541/109d7719e323/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17c5/12149541/d5f6cd6d3614/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17c5/12149541/fe6a9f53813d/gr3.jpg

相似文献

1
Small lymphocytic lymphoma presenting as bilateral medial lower eyelid ectropion.表现为双侧下睑内侧外翻的小淋巴细胞淋巴瘤。
Am J Ophthalmol Case Rep. 2025 May 9;39:102352. doi: 10.1016/j.ajoc.2025.102352. eCollection 2025 Sep.
2
Mid Forehead Brow Lift额中眉提升术
3
Lower eyelid involutional ectropion repair with lateral tarsal strip and internal retractor reattachment with full-thickness eyelid sutures.采用外侧睑板条联合全层眼睑缝线行内眦韧带重新附着术修复下睑退行性外翻。
Ophthalmic Plast Reconstr Surg. 2014 Sep-Oct;30(5):424-6. doi: 10.1097/IOP.0000000000000218.
4
Correction of involutional lower eyelid medial ectropion with transconjunctival approach retractor plication and lateral tarsal strip.经结膜入路牵开器折叠术联合外侧睑板条法矫正老年性下睑内侧外翻
Acta Ophthalmol Scand. 2006 Apr;84(2):246-9. doi: 10.1111/j.1600-0420.2005.00603.x.
5
A New Surgical Method for Medial Ectropion Repair: Fixing the Lower Eyelid Retractor to the Back of the Tarsal Plate.一种治疗内眦赘皮的新手术方法:将下眼睑提肌固定于睑板后。
J Craniofac Surg. 2021;32(1):e55-e58. doi: 10.1097/SCS.0000000000006922.
6
Modified lateral tarsal strip for involutional entropion and ectropion surgery.改良外侧睑板条用于老年性睑内翻和睑外翻手术。
Graefes Arch Clin Exp Ophthalmol. 2017 Mar;255(3):619-625. doi: 10.1007/s00417-016-3536-2. Epub 2016 Nov 5.
7
Change in Lower Eyelid Contour Following Ectropion Repair With Lateral Tarsal Strip.外侧睑板条法修复下眼睑外翻后下眼睑轮廓的变化。
Ophthalmic Plast Reconstr Surg. 2020 Nov/Dec;36(6):557-561. doi: 10.1097/IOP.0000000000001634.
8
Lateral tarsal strip procedure for involutional ectropion: A retrospective analysis of 85 cases and a comprehensive literature review.用于退行性睑外翻的睑板条外侧手术:85例回顾性分析及文献综述
Adv Ophthalmol Pract Res. 2021 Sep 9;1(1):100004. doi: 10.1016/j.aopr.2021.100004. eCollection 2021 Nov.
9
Lower-eyelid tarsal ectropion repair with the Putterman ptosis clamp for lower-eyelid conjunctival Mueller's muscle resection and lateral tendon tuck.经皮提上睑肌夹修复下眼睑睑板-结膜 Müller 肌切除术和外侧腱滑车术治疗下眼睑睑缘外翻。
Ophthalmic Plast Reconstr Surg. 2012 May-Jun;28(3):224-7. doi: 10.1097/IOP.0b013e31824a4b0c.
10
Outcomes From Lateral Eyelid Coupling for Facial Paralysis Using the Modified Tarsoconjunctival Flap.改良睑板结膜瓣行外侧眼睑耦合治疗面瘫的疗效。
JAMA Facial Plast Surg. 2018 Sep 1;20(5):381-386. doi: 10.1001/jamafacial.2018.0070.

本文引用的文献

1
Chronic Lymphocytic Leukemia with Orbital and Sinonasal Manifestations.伴有眼眶和鼻窦表现的慢性淋巴细胞白血病
Ear Nose Throat J. 2024 Nov 20:1455613241287013. doi: 10.1177/01455613241287013.
2
Basic immunohistochemistry for lymphoma diagnosis.用于淋巴瘤诊断的基础免疫组织化学
Blood Res. 2022 Apr 30;57(S1):55-61. doi: 10.5045/br.2022.2022037.
3
Richter's Transformation.里希特转化。
Curr Oncol Rep. 2022 Aug;24(8):1081-1090. doi: 10.1007/s11912-022-01274-4. Epub 2022 Apr 6.
4
Chronic Lymphocytic Leukemia.慢性淋巴细胞白血病。
Cold Spring Harb Perspect Med. 2021 Feb 1;11(2):a035220. doi: 10.1101/cshperspect.a035220.
5
Ectropion.睑外翻
Semin Ophthalmol. 2010 May;25(3):59-65. doi: 10.3109/08820538.2010.488570.
6
Ectropion and entropion.睑外翻和睑内翻。
Curr Opin Ophthalmol. 2000 Oct;11(5):345-51. doi: 10.1097/00055735-200010000-00010.
7
A new prognostic classification of chronic lymphocytic leukemia derived from a multivariate survival analysis.一项基于多变量生存分析得出的慢性淋巴细胞白血病新预后分类。
Cancer. 1981 Jul 1;48(1):198-206. doi: 10.1002/1097-0142(19810701)48:1<198::aid-cncr2820480131>3.0.co;2-v.
8
Clinical staging of chronic lymphocytic leukemia.慢性淋巴细胞白血病的临床分期
Blood. 1975 Aug;46(2):219-34.