Rangeiro Ricardina, Lopes Andre, Munsell Mark F, Changule Dercia, Daud Siro, Ferreira Calisto, Ribeiro Magda, Mabota Flora, Luis Elvira, Daniel Agostinho, Tsambe Edgar, Bila Celso, Fontes-Cintra Georgia, Moretti-Marques Renato, Vieira Marcelo, Alvarenga-Bezerra Vanessa, Carrilho Carla, Baker Ellen, Lorenzoni Cesaltina, Schmeler Kathleen M, Salcedo Mila P
Hospital Central de Maputo, Maputo, Mozambique.
A. C. Camargo Cancer Center, São Paulo, Brazil.
JCO Glob Oncol. 2025 Jun;11:e2500024. doi: 10.1200/GO-25-00024. Epub 2025 Jun 11.
Cervical cancer is the most common cancer among women in Mozambique and is a major health burden. Surgery for cervical cancer is currently performed at only one hospital in the country, Maputo Central Hospital. Before 2020, there were no gynecologists in Mozambique trained to care for women with cervical cancer. In 2017, the International Gynecologic Cancer Society (IGCS) started a gynecologic oncology training program in Mozambique, and in 2020, the first three fellows graduated from this program. The main objective of this study was to report the outcomes of patients with cervical cancer who were treated surgically by the three newly trained Mozambican gynecologic oncologists.
We performed a retrospective chart review of women diagnosed with cervical cancer who underwent surgical treatment by the Mozambican gynecologic oncologists between November 2020 and October 2022. The outcome of interest was survival at 2 years.
Thirty-three patients underwent radical hysterectomy with pelvic lymphadenectomy for cervical cancer treatment. The median age at diagnosis was 43 years. After surgery, 15 patients (45%) were dispositioned to surveillance and 18 (55%) were referred for adjuvant treatment with radiotherapy and/or chemotherapy. All patients had follow-up data available, with a median follow-up time of 19 months (range, 0.2 to 37.5). Only one patient died, and the overall survival is 95.7% (95% CI, 87.7% to 100%) at 12.7 months.
The IGCS program has provided training to physicians at Maputo Central Hospital, resulting in surgery for cervical cancer being available to patients in Mozambique. This is an important step in the global elimination of cervical cancer.
宫颈癌是莫桑比克女性中最常见的癌症，也是一项重大的健康负担。目前该国仅有马普托中心医院这一家医院开展宫颈癌手术。2020年之前，莫桑比克没有接受过宫颈癌患者护理培训的妇科医生。2017年，国际妇科癌症协会（IGCS）在莫桑比克启动了一项妇科肿瘤学培训项目，2020年，首批三名学员从该项目毕业。本研究的主要目的是报告由三名新培训的莫桑比克妇科肿瘤学家手术治疗的宫颈癌患者的治疗结果。
我们对2020年11月至2022年10月期间被莫桑比克妇科肿瘤学家诊断为宫颈癌并接受手术治疗的女性进行了回顾性病历审查。感兴趣的结果是2年生存率。
33例患者接受了根治性子宫切除术加盆腔淋巴结清扫术以治疗宫颈癌。诊断时的中位年龄为43岁。手术后，15例患者（45%）接受观察，18例（55%）被转诊接受放疗和/或化疗的辅助治疗。所有患者均有随访数据，中位随访时间为19个月（范围0.2至37.5个月）。仅1例患者死亡，12.7个月时的总生存率为95.7%（95%CI，87.7%至100%）。
IGCS项目为马普托中心医院的医生提供了培训，使莫桑比克的患者能够接受宫颈癌手术。这是全球消除宫颈癌的重要一步。
