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乳腺重建术后加速康复方案的实施:来自法国一家三级中心的经验教训

Implementation of enhanced recovery after surgery in breast reconstruction: Lessons from a French tertiary center.

作者信息

Vinel Alexandre, Babre Florence, Dannepond Antoine, Commeny Julie, Adam Diane, Delgove Anaïs, Michot Audrey

机构信息

Plastic and Reconstructive Surgery Department, University hospital of Bordeaux, Bordeaux, France.

Department of Anesthesia-Intensive Care, Bergonié Institute, Bordeaux, France.

出版信息

Surg Oncol. 2025 Aug;61:102250. doi: 10.1016/j.suronc.2025.102250. Epub 2025 Jun 7.

Abstract

INTRODUCTION

Enhanced Recovery After Surgery (ERAS) programs have significantly improved postoperative outcomes across various surgical disciplines. In April 2022, an ERAS protocol tailored for patients undergoing DIEP free flap breast reconstruction was implemented at the Bordeaux Cancer Center, France. This study aimed to assess the impact of this protocol on length of stay (LOS), complication rates, and compliance with protocol items.

MATERIAL AND METHODS

A retrospective pre-post observational study was conducted, including 56 consecutive patients who underwent DIEP flap reconstruction at the Bergonié Institute between September 2020 and April 2023. Twenty-eight patients received conventional perioperative care, while 28 patients were managed under the ERAS protocol. Outcomes assessed included LOS, early and 90-day postoperative complications, and adherence to the protocol's 20 key items.

RESULTS

Median LOS was comparable between groups, at 4.5 days pre-ERAS and 5 days post-ERAS (p = 0.52). Early and 90-day complication rates showed no significant differences. The average compliance with protocol items was 14.2 out of 20 per patient, with 35 % of recommendations followed in less than 66 % of cases.

CONCLUSION

The initial evaluation of the ERAS program showed no significant reduction in LOS or morbidity, primarily due to suboptimal adherence. These findings highlight the importance of optimizing compliance with protocol recommendations to further improve recovery outcomes, reduce LOS and potentially lower overall healthcare costs.

摘要

引言

术后加速康复(ERAS)计划显著改善了各个外科领域的术后效果。2022年4月,法国波尔多癌症中心实施了一项针对接受腹壁下动脉穿支游离皮瓣乳房重建患者的ERAS方案。本研究旨在评估该方案对住院时间(LOS)、并发症发生率以及方案项目依从性的影响。

材料与方法

进行了一项回顾性前后对照观察性研究,纳入了2020年9月至2023年4月期间在贝戈涅研究所连续接受腹壁下动脉穿支皮瓣重建的56例患者。28例患者接受传统围手术期护理,而28例患者按照ERAS方案进行管理。评估的结果包括住院时间、术后早期和90天并发症,以及对方案20项关键项目的依从性。

结果

两组的中位住院时间相当,ERAS前为4.5天,ERAS后为5天(p = 0.52)。早期和90天并发症发生率无显著差异。每位患者对方案项目的平均依从性为20项中的14.2项,35%的建议在不到66%的病例中得到遵循。

结论

ERAS计划的初步评估显示住院时间或发病率没有显著降低,主要原因是依从性欠佳。这些发现凸显了优化对方案建议的依从性对于进一步改善康复结果、缩短住院时间并可能降低总体医疗成本的重要性。

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