Ma Boya, Zhao Wenshi, Wu Yu, Wan Xiangyue, Zhao Hang, Wang Yongdan, Lang Jihui, Li Jinying, Liu Yang
Key Laboratory of Preparation and Application of Environmental Friendly Materials of the Ministry of Education, Jilin Normal University, Changchun, 130103, PR China; Key Laboratory of Functional Materials Physics and Chemistry of the Ministry of Education, Jilin Normal University, Changchun, 130103, PR China.
Key Laboratory of Functional Materials Physics and Chemistry of the Ministry of Education, Jilin Normal University, Changchun, 130103, PR China.
Talanta. 2026 Jan 1;296:128446. doi: 10.1016/j.talanta.2025.128446. Epub 2025 Jun 10.
Tetracycline (TC), a widely used broad-spectrum antibiotic for treating bacterial infections, poses significant risks to human health and ecological environments caused by extensive abuse. Hence, sensitive detection and efficient degradation of TC are crucial for protecting both human health and ecological environment. In this work, a multifunctional Z-scheme CuO@Ag/g-CN heterojunction was designed and constructed in order to achieve both ultrasensitive surface-enhanced Raman scattering (SERS) detection and efficient photocatalytic degradation of TC. The influence of the Ag content on the SERS performance was investigated using the finite-difference time-domain (FDTD) method. The charge transfer (CT) mechanism was deduced by band gap and Fermi level calculations. The results showed that the synergistic effect of electromagnetic enhancement (EM) and chemical enhancement (CE) contributed to the excellent SERS sensitivity of CuO@Ag/g-CN nanocomposites (NCs). The limit of detection (LOD) for TC using CuO@Ag/g-CN NCs as SERS substrate was as low as 10 M, and the SERS substrate could also be used to TC detection in real milk samples. In addition, CuO@Ag/g-CN NCs could also act as the efficient photocatalyst to achieve the removal of TC with degradation rate of 94 % under visible light irradiation. Especially, the CuO@Ag/g-CN NCs maintained excellent photocatalytic performance even after six cycles. Possible degradation pathways and photocatalytic degradation mechanism of TC catalyzed by CuO@Ag/g-CN NCs were also proposed. This multifunctional Z-scheme CuO@Ag/g-CN NCs should thus have great potential for the integration of ultrasensitive SERS detection and efficient degradation of antibiotics.
四环素（TC）是一种广泛用于治疗细菌感染的广谱抗生素，由于其广泛滥用，对人类健康和生态环境构成了重大风险。因此，灵敏检测和高效降解四环素对于保护人类健康和生态环境至关重要。在这项工作中，设计并构建了一种多功能Z型CuO@Ag/g-CN异质结，以实现超灵敏的表面增强拉曼散射（SERS）检测和四环素的高效光催化降解。采用时域有限差分（FDTD）方法研究了银含量对SERS性能的影响。通过带隙和费米能级计算推导了电荷转移（CT）机制。结果表明，电磁增强（EM）和化学增强（CE）的协同作用有助于CuO@Ag/g-CN纳米复合材料（NCs）具有优异的SERS灵敏度。以CuO@Ag/g-CN NCs作为SERS基底检测四环素的检测限低至10⁻¹¹ M，该SERS基底还可用于实际牛奶样品中四环素的检测。此外，CuO@Ag/g-CN NCs还可作为高效光催化剂，在可见光照射下实现四环素的去除，降解率达94%。特别是，CuO@Ag/g-CN NCs即使在六个循环后仍保持优异的光催化性能。还提出了CuO@Ag/g-CN NCs催化四环素可能的降解途径和光催化降解机制。因此，这种多功能Z型CuO@Ag/g-CN NCs在超灵敏SERS检测和抗生素高效降解的集成方面具有巨大潜力。
