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胸腺瘤和胸腺癌,第2.2025版,美国国立综合癌症网络(NCCN)肿瘤学临床实践指南

Thymomas and Thymic Carcinomas, Version 2.2025, NCCN Clinical Practice Guidelines In Oncology.

作者信息

Riely Gregory J, Wood Douglas E, Loo Billy W, Aisner Dara L, Akerley Wallace, Bauman Jessica R, Bharat Ankit, Chang Joe Y, Chirieac Lucian R, DeCamp Malcolm, Desai Aakash, Dilling Thomas J, Dowell Jonathan, Durm Gregory A, Gettinger Scott, Grotz Travis E, Gubens Matthew A, Juloori Aditya, Lackner Rudy P, Lanuti Michael, Lin Jules, Lovly Christine M, Maldonado Fabien, Morgensztern Daniel, Mullikin Trey C, Ng Thomas, Owen Dawn, Owen Dwight H, Patel Sandip P, Patil Tejas, Polanco Patricio M, Riess Jonathan, Shapiro Theresa A, Singh Aditi P, Stevenson James, Tam Alda, Tanvetyanon Tawee, Yanagawa Jane, Yang Stephen C, Yau Edwin, Gregory Kristina, Hang Lisa

机构信息

1Memorial Sloan Kettering Cancer Center.

2Fred Hutchinson Cancer Center.

出版信息

J Natl Compr Canc Netw. 2025 Jun;23(6):255-269. doi: 10.6004/jnccn.2025.0027.

DOI:10.6004/jnccn.2025.0027
PMID:40499586
Abstract

Thymomas and thymic carcinomas are rare mediastinal tumors that originate in the thymus. Patients with thymoma may experience symptoms associated with autoimmune paraneoplastic diseases (such as myasthenia gravis), which typically do not occur in patients with thymic carcinoma. The NCCN Guidelines for Thymomas and Thymic Carcinomas provide guidance for the diagnosis, treatment, and surveillance of patients with thymoma and thymic carcinoma. Involvement of a multidisciplinary team with experience treating thymomas and thymic carcinomas is highly recommended.

摘要

胸腺瘤和胸腺癌是起源于胸腺的罕见纵隔肿瘤。胸腺瘤患者可能会出现与自身免疫性副肿瘤性疾病(如重症肌无力)相关的症状,而胸腺癌患者通常不会出现这些症状。《NCCN胸腺瘤和胸腺癌临床实践指南》为胸腺瘤和胸腺癌患者的诊断、治疗及监测提供了指导。强烈建议由具备治疗胸腺瘤和胸腺癌经验的多学科团队参与治疗。

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Thymomas and Thymic Carcinomas, Version 2.2025, NCCN Clinical Practice Guidelines In Oncology.胸腺瘤和胸腺癌,第2.2025版,美国国立综合癌症网络(NCCN)肿瘤学临床实践指南
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Cancers (Basel). 2025 Jul 30;17(15):2513. doi: 10.3390/cancers17152513.
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Complete pathologic response after concomitant pembrolizumab and radiotherapy in a patient with pretreated metastatic thymic carcinoma: a case report.
帕博利珠单抗与放疗联合治疗预处理后的转移性胸腺癌患者获得完全病理缓解:一例报告
Mediastinum. 2025 Jun 25;9:21. doi: 10.21037/med-25-16. eCollection 2025.
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Surveillance of thymic epithelial tumors (TETs)-a narrative review.胸腺上皮肿瘤(TETs)的监测——一篇叙述性综述
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ESMO Open. 2025 Jun;10(6):105301. doi: 10.1016/j.esmoop.2025.105301. Epub 2025 Jun 1.