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[利用核磁共振断层扫描对心脏进行成像。I:断层扫描]

[Imaging of the heart using nuclear magnetic resonance tomography. I: Tomography].

作者信息

Lanzer P A, Botvinick E H, Higgins C B

出版信息

Z Kardiol. 1985 Aug;74(8):423-34.

PMID:4049993
Abstract

Magnetic resonance (MR) is a new concept in the diagnostics of the cardiovascular system. The basic principle of MR is nuclear magnetism. MR tomography is based on induction and spatial encoding of a nuclear magnetic resonance signal. Due to the high tissue concentration and MR sensitivity, medical MR imaging chiefly uses protons of water, 1H. MR tomography of protons presents highly contrasted images of soft tissue organs with spatial resolution in millimeters. Parametric analysis of the MR signal enables quantitative assessments of physico-chemical tissue properties, blood flow and perfusion. The method is noninvasive and without serious biological side effects. Ionising radiation or traditional contrast agents are not utilized. Using conventional ECG synchronized MR tomography the cardiac and great vessels anatomy are superbly resolved, exceptions being the resolution of coronary vasculature and cardiac valve apparatus. The excellent spatial resolution and flexible spatial image orientation are important advantages of quantitative assessment of cardiac function by MR imaging. Preliminary studies demonstrated clinical utility of tomographic assessments of T1 and T2 relaxation parameters as well as phase angle analysis for definition of myocardial ischemia, blood flow rates and wall motion dynamics. The first comparative studies between imaging modalities in diagnostics of specific cardiac disorders point to a superior anatomic resolution of the heart and vascular morphology by MR tomography. The utilization of MR tomography in cardiovascular medicine is new and it would be premature to assign a definite value to this costly technique in clinical evaluations of patients with heart disease. However, there is unequivocal evidence that MR technology will play a decisive role in cardiology in the future, and MR imaging already represents significant progress in the evaluation of patients with cardiac disease.

摘要

磁共振成像(MR)是心血管系统诊断中的一个新概念。MR的基本原理是核磁性。MR断层扫描基于核磁共振信号的感应和空间编码。由于组织中氢质子浓度高且对MR敏感,医学MR成像主要使用水的质子,即1H。质子的MR断层扫描能呈现软组织器官的高对比度图像,空间分辨率可达毫米级。对MR信号进行参数分析可对组织的物理化学性质、血流和灌注进行定量评估。该方法是非侵入性的,且无严重的生物学副作用。不使用电离辐射或传统造影剂。使用传统的心电图同步MR断层扫描,心脏和大血管的解剖结构能得到极好的显示,冠状动脉血管和心脏瓣膜装置的显示除外。MR成像在定量评估心脏功能方面,其出色的空间分辨率和灵活的空间图像取向是重要优势。初步研究表明,对T1和T2弛豫参数进行断层扫描评估以及进行相角分析以确定心肌缺血、血流速度和壁运动动力学具有临床实用性。在特定心脏疾病诊断中,不同成像方式之间的首次比较研究表明,MR断层扫描在心脏和血管形态的解剖分辨率方面更具优势。MR断层扫描在心血管医学中的应用尚新,在对心脏病患者进行临床评估时,就给这种成本高昂的技术赋予明确价值还为时过早。然而,有明确证据表明,MR技术未来将在心脏病学中发挥决定性作用,并且MR成像在心脏病患者评估中已代表了重大进展。

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