Kholodov S A, Shelkovskiĭ V N, Platonova T K
Zh Vopr Neirokhir Im N N Burdenko. 1985 Jul-Aug(4):18-22.
The fibrinolytic activity of the cerebrospinal fluid and common venous blood flow was studied in 28 patients with ruptured aneurysms of cerebral arteries. Recurrent hemorrhage from the aneurysm was encountered in 8 of 11 patients with increased fibrinolytic activity of the cerebrospinal fluid but in none of the patients with absence of fibrinolysis in the cerebrospinal fluid. At the same time, intensified fibrinolytic activity was found in the common venous blood flow. It is suggested that the lysis of the clot at the site of the rupture of the aneurysmal sac is due to local fibrinolysis in the cerebrospinal fluid. Arterial spasm was detected in most patients with increased fibrinolysis in the fluid, and the severity of the general condition was graded III-V after Hunt and Hess.
对28例脑动脉动脉瘤破裂患者的脑脊液和体静脉血流的纤溶活性进行了研究。脑脊液纤溶活性增加的11例患者中有8例出现动脉瘤复发性出血，而脑脊液无纤溶现象的患者中无一例出现复发性出血。同时，在体静脉血流中发现纤溶活性增强。提示动脉瘤囊破裂部位的血凝块溶解是由于脑脊液中的局部纤溶作用。大多数脑脊液纤溶活性增加的患者检测到动脉痉挛，根据Hunt和Hess分级，患者一般状况的严重程度为III - V级。
