Leclercq M, Harmant J, de Barsy T
Acta Neurol Belg. 1985 Aug-Oct;85(4):202-21.
The literature contains few reports of investigations on the mental state of subjects with Friedreich's ataxia. Most are based on clinical findings and lead to differing conclusions. For some authors the neurological disease is associated with mental deficits of varying magnitude, for others the mental state of the patients is accompanied by any deficit. The authors discuss five cases and try to supplement clinical findings with a series of psychometric tests in three areas: intellectual efficiency, higher cortical functions and elements of personality. The clinical and psychometric results are summarized in a grid comprising the main psychopathological symptoms attached to cerebral organic suffering (psycho-organic syndrome). Comparison of the results with medical data confirm that, in Friedreich's ataxia, there are no specific disorders characteristic of a psycho-organic syndrome. Lastly, the authors discuss certain hypotheses (concerning methods used, precocious appearance of symptoms and reactions to the disease) which try to explain the divergence of conclusions reached in the literature for this type of study.
关于弗里德赖希共济失调患者心理状态的研究报告在文献中较少见。大多数研究基于临床发现，得出了不同的结论。对于一些作者来说，这种神经疾病与不同程度的智力缺陷有关，而对于另一些作者来说，患者的心理状态伴有任何缺陷。作者讨论了五个病例，并试图通过在三个方面进行一系列心理测试来补充临床发现：智力效率、高级皮层功能和人格要素。临床和心理测试结果总结在一个表格中，该表格包含与脑器质性病变相关的主要精神病理症状（精神器质性综合征）。将结果与医学数据进行比较证实，在弗里德赖希共济失调中，不存在精神器质性综合征特有的特定障碍。最后，作者讨论了某些假设（关于所使用的方法、症状的早熟出现以及对疾病的反应），这些假设试图解释这类研究在文献中得出的结论的差异。
