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妊娠性化脓性肉芽肿:一例报告。

Pyogenic granuloma gravidarum: A case report.

作者信息

Goh Ruth S, Peh Wee Ming, Keng Christopher Goh Hood

机构信息

Faculty of Medicine, Imperial College London, London, United Kingdom.

Department of Radiology, Parkway Hospitals, Singapore.

出版信息

Case Rep Womens Health. 2025 May 24;46:e00716. doi: 10.1016/j.crwh.2025.e00716. eCollection 2025 Jun.

DOI:10.1016/j.crwh.2025.e00716
PMID:40503444
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12158557/
Abstract

Pyogenic granuloma gravidarum (PGG) is a benign fibrovascular lesion arising during pregnancy. This report concerns a woman in her third trimester of pregnancy with recurrent left epistaxis and a swelling in her left nostril. She was diagnosed with PGG via magnetic resonance imaging (MRI) and nasoendoscopy. The lesion was managed conservatively and the neonate was delivered without complication at 37 weeks of gestation. Evidence shows that MRI is superior to computerised tomography (CT) in the assessment of soft-tissue masses, but there is a paucity of MRI PGG imaging in the literature. This report shows that MRI, together with the clinical context, is adequate to make a diagnosis of PGG. This was a rare case of a nasal lesion that was allowed to involute conservatively, hence avoiding the potential complications of surgery. This appears to be the first published report to include a follow-up to a successful second pregnancy and delivery without the recurrence of PGG.

摘要

妊娠性化脓性肉芽肿(PGG)是一种在孕期出现的良性纤维血管病变。本报告涉及一名妊娠晚期妇女,她反复出现左侧鼻出血且左侧鼻孔有肿胀。通过磁共振成像(MRI)和鼻内镜检查,她被诊断为PGG。对该病变进行了保守处理,妊娠37周时新生儿顺利分娩,无并发症。有证据表明,在评估软组织肿块方面,MRI优于计算机断层扫描(CT),但文献中关于PGG的MRI成像较少。本报告表明,结合临床情况,MRI足以诊断PGG。这是一例罕见的鼻腔病变,通过保守治疗使其消退,从而避免了手术可能带来的并发症。这似乎是首篇发表的包含对成功的第二次妊娠和分娩进行随访且PGG未复发的报告。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7012/12158557/70629bcaff1b/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7012/12158557/70629bcaff1b/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7012/12158557/70629bcaff1b/gr1.jpg

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1
Pyogenic granuloma gravidarum: A case report.妊娠性化脓性肉芽肿:一例报告。
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本文引用的文献

1
Pyogenic granuloma gravidarum: a case in the nasal cavity and the use of MRI as a preoperative surgical aide.妊娠性化脓性肉芽肿:鼻腔一例及磁共振成像作为术前手术辅助手段的应用
BMJ Case Rep. 2019 May 28;12(5):e225803. doi: 10.1136/bcr-2018-225803.
2
Intranasal Lobular Capillary Hemangioma with Multiple Sites of Origin during Pregnancy: A Case Report and Literature Review.孕期起源于多个部位的鼻内小叶状毛细血管瘤:一例报告及文献复习
Case Rep Otolaryngol. 2018 Sep 18;2018:7413918. doi: 10.1155/2018/7413918. eCollection 2018.
3
Large pregnancy-associated pyogenic granuloma: a case report.
巨大妊娠相关性化脓性肉芽肿:一例报告
J Obstet Gynaecol. 2019 Feb;39(2):265-267. doi: 10.1080/01443615.2018.1441270. Epub 2018 Mar 21.
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Granuloma gravidarum: management.
J Obstet Gynaecol. 2012 Nov;32(8):805. doi: 10.3109/01443615.2012.709287.
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Oral pregnancy tumor.口腔妊娠瘤
Contemp Clin Dent. 2010 Jul;1(3):190-2. doi: 10.4103/0976-237X.72792.
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Lobular capillary haemangioma of the nasal cavity during pregnancy.妊娠期鼻腔小叶状毛细血管瘤
J Laryngol Otol. 2011 Sep;125(9):973-7. doi: 10.1017/S0022215111001654. Epub 2011 Jul 12.
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Treatment options for cutaneous pyogenic granulomas: a review.皮肤化脓性肉芽肿的治疗选择:综述。
J Plast Reconstr Aesthet Surg. 2011 Sep;64(9):1216-20. doi: 10.1016/j.bjps.2010.12.021. Epub 2011 Feb 11.
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Magnetic resonance imaging of sinonasal malignancies.鼻窦恶性肿瘤的磁共振成像
Top Magn Reson Imaging. 2007 Aug;18(4):259-67. doi: 10.1097/RMR.0b013e31815711b7.
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Oral pyogenic granuloma: a review.口腔化脓性肉芽肿:综述
J Oral Sci. 2006 Dec;48(4):167-75. doi: 10.2334/josnusd.48.167.
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Nasal pyogenic granuloma.鼻化脓性肉芽肿。
Otolaryngol Head Neck Surg. 2007 Jan;136(1):130-1. doi: 10.1016/j.otohns.2006.07.031.