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Preoperative CD11c hi atypical memory B cells are associated with postoperative delirium.

作者信息

Tan Siyou, Chen Wenyan, Zhao Yiming, Yuan Xingxing, Li Jieqiong, Yang Ying, Tang Cheng, Rong Mingqiang, Pan Bingbing, Kong Gaoyin, Wei Lai, Xie Yubo

机构信息

Department of Anesthesiology, Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha, China.

The National and Local Joint Engineering Laboratory of Animal Peptide Drug Development, College of Life Sciences, Hunan Normal University, Changsha, China.

出版信息

Int J Surg. 2025 Sep 1;111(9):6494-6496. doi: 10.1097/JS9.0000000000002753. Epub 2025 Jun 12.

DOI:10.1097/JS9.0000000000002753
PMID:40503783
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12430744/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7462/12430744/d38a81449874/js9-111-6494-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7462/12430744/d38a81449874/js9-111-6494-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7462/12430744/d38a81449874/js9-111-6494-g001.jpg

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Preoperative CD11c hi atypical memory B cells are associated with postoperative delirium.术前CD11c高表达的非典型记忆B细胞与术后谵妄相关。
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2
Phosphatidylcholine-specific B cells are enriched among atypical CD11c and CD21 memory B cells in antiphospholipid syndrome.在抗磷脂综合征中，磷脂酰胆碱特异性B细胞在非典型CD11c和CD21记忆B细胞中富集。
Front Immunol. 2025 Jun 3;16:1585953. doi: 10.3389/fimmu.2025.1585953. eCollection 2025.
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本文引用的文献

1
Incidence and risk factors of postoperative delirium in elderly surgical patients 2023.2023年老年外科手术患者术后谵妄的发病率及危险因素
Sci Rep. 2025 Jan 9;15(1):1400. doi: 10.1038/s41598-024-84554-2.
2
Correlation of preoperative frailty with postoperative delirium and 1-year mortality in Chinese geriatric patients undergoing non-cardiac surgery: a prospective observational cohort study.中国老年非心脏手术患者术前衰弱与术后谵妄及1年死亡率的相关性：一项前瞻性观察队列研究
Int J Surg. 2025 Jan 1;111(1):1576-1579. doi: 10.1097/JS9.0000000000002042.
3
Effects of esketamine on postoperative negative emotions and early cognitive disorders in patients undergoing non-cardiac thoracic surgery: A randomized controlled trial.
依托咪酯对非心脏胸科手术患者术后负性情绪及早期认知障碍的影响：一项随机对照试验。
J Clin Anesth. 2024 Aug;95:111447. doi: 10.1016/j.jclinane.2024.111447. Epub 2024 Mar 23.
4
Immune aging - A mechanism in autoimmune disease.免疫衰老——自身免疫性疾病的一种机制。
Semin Immunol. 2023 Sep;69:101814. doi: 10.1016/j.smim.2023.101814. Epub 2023 Aug 4.
5
Memory B cells.记忆B细胞。
Nat Rev Immunol. 2024 Jan;24(1):5-17. doi: 10.1038/s41577-023-00897-3. Epub 2023 Jul 3.
6
Extremes of baseline cognitive function determine the severity of delirium: a population study.基线认知功能的极端情况决定了谵妄的严重程度：一项人群研究。
Brain. 2023 May 2;146(5):2132-2141. doi: 10.1093/brain/awad062.
7
Neural autoantibodies in delirium.谵妄中的神经自身抗体。
J Autoimmun. 2021 Dec;125:102740. doi: 10.1016/j.jaut.2021.102740. Epub 2021 Oct 28.
8
Delirium triggered by COVID-19 vaccine in an elderly patient.一名老年患者中由新冠疫苗引发的谵妄
Geriatr Gerontol Int. 2021 Jun;21(6):540. doi: 10.1111/ggi.14163. Epub 2021 Apr 8.
9
Autoimmune Encephalopathy for Psychiatrists: When to Suspect Autoimmunity and What to Do Next.精神科医生应了解的自身免疫性脑病：何时怀疑自身免疫性疾病以及接下来该怎么做。
Psychosomatics. 2017 May-Jun;58(3):228-244. doi: 10.1016/j.psym.2017.02.014. Epub 2017 Mar 2.