Analysis of skeletal muscle capillarization: methodological problems.

Capillarization of skeletal muscle has been studied on the same muscle with different methods. Capillary/muscle fibre ratio, number of muscle fibres in contact with capillaries, capillary density in a unit area, capillary density on the muscle fibre surface were determined. The various methods gave different numerical data. Determination of capillary/muscle fibre ratio seemed to be the most reliable index of the changes in pathological conditions.