McPherson Jacob I, Miecznikowski Jeffrey C, Chizuk Haley, Sparks Patrick, Leddy John J, Haider Mohammad N, Stavisky Christopher J
Department of Rehabilitation Science, School of Public Health and Health Professions, State University of New York at Buffalo, Buffalo, New York, United States of America.
Department of Biostatistics, School of Public Health and Health Professions, State University of New York at Buffalo, Buffalo, New York, United States of America.
PLoS One. 2025 Jun 12;20(6):e0325701. doi: 10.1371/journal.pone.0325701. eCollection 2025.
Work-related concussion (WRC) is a common occupational injury that has received far less research attention compared to sport-related concussion (SRC). WRC results in prolonged lost time claims, adversely influences perceived life roles, and negatively impacts personal and family finances. WRC also affects workforce capacity in industries that are already facing worker shortages (e.g., construction, manufacturing, healthcare, etc.). Targeted heart rate aerobic exercise (THRAE) has emerged as an effective treatment for speeding recovery from SRC and for reducing the incidence of persisting post-concussive symptoms (PPCS). The aim of this proposed study is to explore the feasibility of THRAE in adults with WRC as there are very few interventions that have been rigorously studied in this population.
We describe a feasibility trial to implement THRAE in individuals with WRC. While this study will not test specific hypotheses related to effectiveness, it will provide key information related to adherence, safety, and psychosocial factors related to adherence and participation. Additionally, this study will provide mean and standard deviation values for the measures applied to this novel population to inform power analyses for larger-scale trials.
Clinicaltrials.gov NCT06263179.
与工作相关的脑震荡（WRC）是一种常见的职业伤害，与运动相关的脑震荡（SRC）相比，受到的研究关注要少得多。WRC导致长期的误工索赔，对人们所感知的生活角色产生不利影响，并对个人和家庭财务产生负面影响。WRC还影响到那些已经面临劳动力短缺的行业（如建筑、制造、医疗保健等）的劳动力规模。有针对性的心率有氧运动（THRAE）已成为一种有效的治疗方法，可加速SRC的恢复并降低持续性脑震荡后症状（PPCS）的发生率。本拟议研究的目的是探讨THRAE对患有WRC的成年人的可行性，因为在这一人群中经过严格研究的干预措施非常少。
我们描述了一项在患有WRC的个体中实施THRAE的可行性试验。虽然本研究不会测试与有效性相关的具体假设，但它将提供与依从性、安全性以及与依从性和参与相关的社会心理因素有关的关键信息。此外，本研究将为应用于这一新型人群的测量提供均值和标准差数值，以为更大规模试验的功效分析提供信息。
Clinicaltrials.gov NCT06263179。
