Sanchez Blanque A, Fernandez Canti G, Gimenez Morales J C, Juste Rullo G
Acta Psychiatr Belg. 1985 May-Jun;85(3):406-15.
The authors have studied 89 depressed patients diagnosed according to three different systems: DSM-III, Kiloh and Garside, Winokur. They administered 1 mg of Dexamethasone at 11 pm; blood samples were taken at 8 am and 8 pm the next day. They find the most significant differences in cortisol levels according to the DSM classification whereas there are no significant differences according to the Winokur classification. They refer the great variance obtained in the endogenous groups to a high incidence of suppressors in these non-suppressor groups. In 26 non-depressed patients, they found 10 non-suppressors. According to the authors, these results demonstrate the importance of DST and other biological tests in the reformation of nosology in psychiatry.
作者们根据三种不同的系统（DSM-III、基洛和加赛德、维诺克）对89名抑郁症患者进行了研究。他们于晚上11点给予1毫克地塞米松；次日上午8点和晚上8点采集血样。他们发现，根据DSM分类，皮质醇水平存在最显著差异，而根据维诺克分类则无显著差异。他们将内源性组中获得的巨大差异归因于这些非抑制组中抑制物的高发生率。在26名非抑郁症患者中，他们发现了10名非抑制者。作者们认为，这些结果证明了地塞米松抑制试验（DST）和其他生物学检测在精神病学分类学改革中的重要性。
