Saunders John, Deering Joseph, Dewsnap Claire, Drayton Rachel, Gilmore John, Grant Alison, Hunt Dwayne-Wilson, Kohli Manik, Lyons Fiona, Mohammed Hamish, Samba Phil, Weil Benjamin, White John, Medland Nicholas, Fifer Helen
Blood Safety, Hepatitis, STIs and HIV Division, UK Health Security Agency, London, UK.
HCRG Care Group, Runcorn, UK.
Int J STD AIDS. 2025 Jun 12:9564624251352053. doi: 10.1177/09564624251352053.
This guideline provides evidence-based recommendations for the use of doxycycline post exposure prophylaxis (doxyPEP) for the prevention of syphilis. DoxyPEP should be part of a comprehensive approach to the prevention of STIs, along with condom use, appropriate HIV prevention interventions, vaccination, STI testing, treatment and management, and appropriate risk reduction advice and psychological interventions if indicated.
本指南为使用多西环素暴露后预防(doxyPEP)预防梅毒提供循证建议。多西环素暴露后预防应作为性传播感染综合预防方法的一部分,同时包括使用避孕套、适当的艾滋病毒预防干预措施、疫苗接种、性传播感染检测、治疗与管理,以及在有指征时提供适当的风险降低建议和心理干预措施。