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既往髋臼周围截骨术对发育性髋关节发育不良患者全髋关节置换术疗效的影响。

Impact of Prior Periacetabular Osteotomy on Total Hip Arthroplasty Outcomes in Patients with Developmental Dysplasia of the Hip.

作者信息

Czwojdziński Adam, Leśniak Jakub, Sionek Andrzej, Grzelecki Dariusz, Czubak Jarosław

机构信息

Department of Orthopedics, Pediatric Orthopedics and Traumatology, Centre of Postgraduate Medical Education, Professor Adam Gruca Orthopedic and Trauma Teaching Hospital, Konarskiego 13, 05-400 Otwock, Poland.

Department of Orthopedics and Rheumoorthopedics, Centre of Postgraduate Medical Education, Professor Adam Gruca Orthopedic and Trauma Teaching Hospital, Konarskiego 13, 05-400 Otwock, Poland.

出版信息

J Clin Med. 2025 May 23;14(11):3661. doi: 10.3390/jcm14113661.

Abstract

This study aims to demonstrate the challenges during the treatment of patients with osteoarthritis due to the development of dysplasia, which can be faced by surgeons who treat patients with THA. Our objective is to present our findings from a comparison of patients who underwent total hip arthroplasty (THA) for osteoarthritis secondary to developmental dysplasia of the hip (DDH), with or without a prior periacetabular osteotomy (PAO). We divided patients into two groups. Group A was adolescents who underwent periacetabular osteotomy and further THA in the orthopedic center (29 hips), and Group B was adolescents who underwent THA without PAO but suffered from DDH (24 hips). We measured blood loss, cup size, cup positioning, cup coverage, inclination and anteversion of the cup, duration of surgery, clinical scores, time of hospitalization, and the presence of ossification. The mHHS score demonstrated significant differences (group A: 89 points vs. group B: 91 points; = 0.03). The blood loss was expressed in the difference in Hb concentration preoperatively and on the 3rd postoperative day, which was higher by 0.85 mg/dL in group A (group A: 4.4 mg/dl vs. group B: 3.55 mg/dL; = 0.004). Also, the value of HCT on the 3rd postoperative day was significantly lower in group A (group A: 27% vs. group B: 29.5%; = 0.02). Radiological measurements showed a statistically significant difference in the Brooker scale ( = 0.005). Thirteen patients from group A after THA expressed first-grade ossifications or higher, and two patients from group B had first- and second-grade ossifications. Furthermore, a notably larger distalization was observed after the PAO procedure compared to those who underwent the procedure without PAO previously (79 mm [IQR = 73-83 mm] vs. 74.5 mm [IQR = 69-77 mm]; = 0.004). Conclusions: Patients reported lower mHHS results, a higher risk of heterotopic ossifications, prosthesis head distalization, and more significant blood loss during the perioperative period after THA in patients who underwent PAO compared to those without a previously performed osteotomy.

摘要

本研究旨在证明发育异常导致骨关节炎患者治疗过程中面临的挑战,这是全髋关节置换术(THA)治疗患者的外科医生可能会遇到的情况。我们的目的是展示对因髋关节发育不良(DDH)继发骨关节炎而接受全髋关节置换术(THA)的患者进行比较的结果,这些患者有或没有先前的髋臼周围截骨术(PAO)。我们将患者分为两组。A组是在骨科中心接受髋臼周围截骨术并进一步接受THA的青少年(29髋),B组是未接受PAO但患有DDH并接受THA的青少年(24髋)。我们测量了失血量、髋臼杯尺寸、髋臼杯位置、髋臼杯覆盖度、髋臼杯倾斜度和前倾角、手术持续时间、临床评分、住院时间以及骨化情况。改良Harris髋关节评分(mHHS)显示出显著差异(A组:89分 vs. B组:91分;P = 0.03)。失血量以术前和术后第3天血红蛋白浓度的差异表示,A组高0.85mg/dL(A组:4.4mg/dl vs. B组:3.55mg/dL;P = 0.004)。此外,术后第3天A组的血细胞比容(HCT)值显著低于B组(A组:27% vs. B组:29.5%;P = 0.02)。影像学测量显示在布鲁克分级(Brooker scale)上有统计学显著差异(P = 0.005)。A组13例THA术后患者出现一级或更高等级的骨化,B组2例患者出现一级和二级骨化。此外,与先前未接受PAO手术的患者相比,PAO手术后观察到明显更大的假体头远端移位(79mm[四分位间距(IQR)=73 - 83mm] vs. 74.5mm[IQR = 69 - 77mm];P = 0.004)。结论:与未进行过截骨术的患者相比,接受PAO的患者在THA术后报告的mHHS结果更低,异位骨化风险更高,假体头远端移位更明显,围手术期失血更显著。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41e7/12155467/ae86dd4af5bd/jcm-14-03661-g001.jpg

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