Yun Ye-Rim, Yeom Ji-Sung, Lee Joon-Seok, Kim Doori, Lee Yoon Jae, Ha In-Hyuk, Kim Do-Young
Department of Acupuncture & Moxibustion, Jaseng Korean Medicine Hospital, Seoul 06110, Republic of Korea.
Jaseng Spine and Joint Research Institute, Jaseng Medical Foundation, Seoul 06110, Republic of Korea.
J Clin Med. 2025 May 25;14(11):3705. doi: 10.3390/jcm14113705.
Spinal deformities, particularly thoracolumbar kyphosis, affect approximately one-third of patients with Parkinson's disease (PD) and significantly impair their quality of life and mobility. Conventional treatments, including levodopa and surgical interventions, have limited efficacy, necessitating alternative therapies. In this report, a 76-year-old woman with PD and severe thoracolumbar kyphosis (TK: 77.7°; sagittal vertical axis [SVA]: 95.55 mm) experienced postural instability and gait impairment. She underwent integrative postural rehabilitation (acupuncture, pharmacopuncture, Chuna spinal manual therapy, thermotherapy, and bodyweight exercises). A 4-week inpatient treatment improved spinal alignment (TK: 61.1°; SVA: 77.84 mm), gait, postural stability (MDS-UPDRS score improved by 3 points), and functional outcomes, with reductions in the Oswestry Disability Index (70 to 31) and pain severity (Numeric Rating Scale: 50 to 40). No adverse events were observed. Integrative postural rehabilitation can mitigate paraspinal muscle atrophy and fatty infiltration by promoting protein synthesis, neurotrophic factor expression, and proprioceptive neuromodulation. Our literature review suggests that proprioceptive stimulation and exercise enhances postural stability and gait, aligning with the outcomes of this case. This report suggests that integrative rehabilitation may improve kyphotic deformities and related motor dysfunctions in patients with PD. Further research is warranted to validate the treatment's efficacy and long-term benefits.
脊柱畸形，尤其是胸腰段后凸，影响约三分之一的帕金森病（PD）患者，并严重损害他们的生活质量和行动能力。包括左旋多巴和手术干预在内的传统治疗方法疗效有限，因此需要替代疗法。在本报告中，一名76岁患有PD和严重胸腰段后凸（胸椎后凸角：77.7°；矢状垂直轴[SVA]：95.55毫米）的女性出现姿势不稳和步态障碍。她接受了综合姿势康复治疗（针灸、药物针灸、脊柱推拿疗法、热疗和体重训练）。为期4周的住院治疗改善了脊柱排列（胸椎后凸角：61.1°；SVA：77.84毫米）、步态、姿势稳定性（MDS-UPDRS评分提高了3分）和功能结果，同时降低了Oswestry功能障碍指数（从70降至31）和疼痛严重程度（数字评分量表：从50降至40）。未观察到不良事件。综合姿势康复可以通过促进蛋白质合成、神经营养因子表达和本体感觉神经调节来减轻椎旁肌萎缩和脂肪浸润。我们的文献综述表明，本体感觉刺激和锻炼可增强姿势稳定性和步态，与该病例的结果一致。本报告表明，综合康复可能改善PD患者的后凸畸形和相关运动功能障碍。有必要进行进一步研究以验证该治疗方法的疗效和长期益处。
