Jin Jian, Long Huibin, Zhang Huiwen, Zhang Chuanhui, Lin Jianhao
Arthritis Clinical and Research Center, Peking University People's Hospital, No.11 Xizhimen South Street, Beijing 100044, China.
Department of Joint and Sports Medicine, Chaoyang Central Hospital, No. 6 Section 2 Chaoyang Avenue, Shuangta District, Chaoyang 122000, China.
Healthcare (Basel). 2025 May 31;13(11):1311. doi: 10.3390/healthcare13111311.
Sarcopenia and buttock pain are highly prevalent in older adults and exert profound negative effects on quality of life. Little is known about the association between sarcopenia and buttock pain.
This study performed cross-sectional and longitudinal analyses based on prospective cohort study data from the 2015 and 2020 waves of the China Health and Retirement Longitudinal Study (CHARLS). A total of 12,884 community-dwelling adults aged ≥45 years were included in the cross-sectional analysis, and 10,511 of these participants, free of buttock pain at baseline, were further investigated to assess incident buttock pain. Sarcopenia status was categorized as non-sarcopenia, possible sarcopenia, and sarcopenia according to the 2019 Asian Working Group for Sarcopenia and the 2021 Chinese consensus criteria. Logistic regression models adjusted for sociodemographic and health-related covariates were performed to estimate associations between sarcopenia status and buttock pain.
After adjusting for covariates, possible sarcopenia, but not sarcopenia, was associated with prevalent buttock pain (OR 1.23, 95% CI 1.03-1.48). After 5 years of follow-up, participants with sarcopenia were more likely to develop incident buttock pain (OR 1.37, 95% CI 1.03-1.81). Among sarcopenia components, poor physical performance was linked to prevalent pain (OR 1.25, 95% CI 1.05-1.50) and low handgrip strength predicted incident pain in males (OR 1.31, 95% CI 1.07-1.60). Appendicular muscle mass was not independently associated with either prevalent or incident buttock pain.
In middle-aged and older Chinese adults, sarcopenia is an independent risk factor for incident buttock pain. Early screening and interventions of sarcopenia may help to mitigate the burden of buttock pain and its associated disability.
肌肉减少症和臀部疼痛在老年人中非常普遍，对生活质量产生深远的负面影响。关于肌肉减少症与臀部疼痛之间的关联，人们知之甚少。
本研究基于中国健康与养老追踪调查（CHARLS）2015年和2020年两轮前瞻性队列研究数据进行横断面和纵向分析。横断面分析共纳入12884名年龄≥45岁的社区居住成年人，其中10511名基线时无臀部疼痛的参与者被进一步调查以评估臀部疼痛的发生情况。根据2019年亚洲肌肉减少症工作组和2021年中国专家共识标准，将肌肉减少症状态分为非肌肉减少症、可能肌肉减少症和肌肉减少症。采用调整了社会人口学和健康相关协变量的逻辑回归模型来估计肌肉减少症状态与臀部疼痛之间的关联。
在调整协变量后，可能肌肉减少症而非肌肉减少症与臀部疼痛患病率相关（比值比1.23，95%置信区间1.03 - 1.48）。经过5年随访，肌肉减少症参与者更有可能出现臀部疼痛（比值比1.37，95%置信区间1.03 - 1.81）。在肌肉减少症的各组成部分中，身体功能较差与疼痛患病率相关（比值比1.25，95%置信区间1.05 - 1.50），男性中握力低预示着疼痛的发生（比值比1.31，95%置信区间1.07 - 1.60）。四肢肌肉量与臀部疼痛患病率或发病率均无独立关联。
在中老年中国成年人中，肌肉减少症是臀部疼痛发生的独立危险因素。早期筛查和干预肌肉减少症可能有助于减轻臀部疼痛及其相关残疾的负担。
