Siew Zhen Yun, Ong Ghee Khang, Khoo Chia Ting, Wong Siew Tung, Voon Kenny
School of Pharmacy, University of Nottingham Malaysia, Semenyih, MYS.
School of Medicine, IMU University, Kuala Lumpur, MYS.
Cureus. 2025 May 12;17(5):e83986. doi: 10.7759/cureus.83986. eCollection 2025 May.
The incidence of appendicitis, an inflammation of the appendix, has been rising significantly in many countries worldwide. Appendicitis may present in various forms, including acute or chronic inflammation, and can manifest as either uncomplicated or complicated conditions, etc. Among these conditions, chronic appendicitis is a rare type of appendiceal inflammation that is less common than acute appendicitis. In this case report, we describe a case of idiopathic appendiceal neuroma, which was initially misdiagnosed as acute gastroenteritis. Diagnosis was further supported by comprehensive laboratory testing, computed tomography and ultrasound imaging, as well as immunohistochemical staining. The patient made a full recovery following a laparoscopic appendectomy. This case highlights appendiceal neuroma as an elusive entity with atypical presentation of appendicitis and chronic histological features, emphasising the critical role of histopathology in establishing a definitive diagnosis.
阑尾炎是阑尾的一种炎症，在世界许多国家，其发病率一直在显著上升。阑尾炎可能以多种形式出现，包括急性或慢性炎症，并且可表现为单纯性或复杂性病症等。在这些病症中，慢性阑尾炎是一种罕见的阑尾炎症类型，比急性阑尾炎少见。在本病例报告中，我们描述了一例特发性阑尾神经瘤病例，该病例最初被误诊为急性肠胃炎。综合实验室检查、计算机断层扫描和超声成像以及免疫组织化学染色进一步支持了诊断。患者在接受腹腔镜阑尾切除术后完全康复。本病例突出了阑尾神经瘤是一种难以捉摸的实体，具有阑尾炎的非典型表现和慢性组织学特征，强调了组织病理学在确立明确诊断中的关键作用。
