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健康成年人上肢神经传导参数的性别差异:一项比较研究。

Gender Differences in Nerve Conduction Parameters of Upper Limb Nerves in Healthy Adults: A Comparative Study.

作者信息

Waghmare Lalitbhushan Shrikrishna, Waghmare Tripti Lalitbhushan, Ambad Ranjit Sidram

机构信息

Department of Physiology Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research Sawangi Meghe, Wardha, Maharashtra, India.

Department of Biochemistry Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research Sawangi Meghe, Wardha, Maharashtra, India.

出版信息

J Pharm Bioallied Sci. 2025 May;17(Suppl 1):S410-S412. doi: 10.4103/jpbs.jpbs_1811_24. Epub 2025 Jan 13.

DOI:10.4103/jpbs.jpbs_1811_24
PMID:40510980
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12156525/
Abstract

BACKGROUND

Nerve conduction studies (NCSs) are essential diagnostic tools for evaluating peripheral nerve function. The influence of gender on nerve conduction parameters, such as conduction velocity, latency, and amplitude, remains a topic of interest. Previous studies have suggested gender differences in nerve conduction but have not provided definitive conclusions.

OBJECTIVE

This study aims to compare the nerve conduction parameters of the upper limb nerves (median, ulnar, and radial) in healthy male and female adults.

MATERIAL AND METHODS

A total of 100 healthy adults (50 males and 50 females) were selected for this study. NCSs were performed on the median, ulnar, and radial nerves, measuring parameters including conduction velocity, latency, and amplitude.

RESULTS

The male group exhibited significantly faster conduction velocities, shorter latencies, and higher amplitudes compared to the female group. The median nerve showed the most pronounced gender differences in conduction velocity.

CONCLUSION

Gender differences in nerve conduction parameters were evident, with males showing faster conduction and higher amplitude. These differences should be considered in clinical practice to improve the accuracy of NCSs and diagnosis.

摘要

背景

神经传导研究(NCSs)是评估周围神经功能的重要诊断工具。性别对神经传导参数(如传导速度、潜伏期和波幅)的影响仍是一个备受关注的话题。以往研究表明神经传导存在性别差异,但尚未得出明确结论。

目的

本研究旨在比较健康成年男性和女性上肢神经(正中神经、尺神经和桡神经)的神经传导参数。

材料与方法

本研究共选取100名健康成年人(50名男性和50名女性)。对正中神经、尺神经和桡神经进行神经传导研究,测量包括传导速度、潜伏期和波幅在内的参数。

结果

与女性组相比,男性组的传导速度明显更快,潜伏期更短,波幅更高。正中神经在传导速度方面表现出最明显的性别差异。

结论

神经传导参数存在性别差异,男性的传导速度更快,波幅更高。在临床实践中应考虑这些差异,以提高神经传导研究和诊断的准确性。

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本文引用的文献

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Sex-Specific Differences in Peripheral Nerve Properties: A Comparative Analysis of Conduction Velocity and Cross-Sectional Area in Upper and Lower Limbs.外周神经特性的性别差异:上肢和下肢传导速度与横截面积的比较分析
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Normative values and factors affecting saphenous nerve responses in a south Asian population: a cross-sectional neurophysiological study at a tertiary care hospital in Pakistan.在巴基斯坦一家三级护理医院进行的横断面神经生理学研究:南亚人群中隐神经反应的正常值和影响因素。
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Nerve Conduction Differences in a Large Clinical Population: The Role of Age and Sex.在一个大型临床人群中神经传导的差异:年龄和性别的作用。
J Neuromuscul Dis. 2023;10(5):925-935. doi: 10.3233/JND-230052.
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The Impact of Estrogen and Estrogen-Like Molecules in Neurogenesis and Neurodegeneration: Beneficial or Harmful?雌激素及雌激素样分子在神经发生与神经退行性变中的作用:有益还是有害?
Front Cell Neurosci. 2021 Mar 8;15:636176. doi: 10.3389/fncel.2021.636176. eCollection 2021.
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Comparison of the Nerve Conduction Parameters in Proximally and Distally Located Muscles Innervated by the Bundles of Median and Ulnar Nerves.正中神经和尺神经束所支配的近端和远端肌肉的神经传导参数比较。
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