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Periodontal Disease牙周病

本文引用的文献

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Antimicrobial peptides in treatment of Stage III Grade B periodontitis: A randomized clinical trial.抗微生物肽治疗 III 期 B 级牙周炎的随机临床试验。
Oral Dis. 2024 Jul;30(5):3376-3385. doi: 10.1111/odi.14786. Epub 2023 Nov 5.
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Osseointegration and antibacterial effect of an antimicrobial peptide releasing mesoporous titania implant.载抗菌肽介孔二氧化钛植入物的骨整合和抗菌效果。
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Efficacy of a proapoptotic peptide towards cancer cells.促凋亡肽对癌细胞的功效。
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Antimicrobial peptides: key components of the innate immune system.抗菌肽：先天免疫系统的关键组成部分。
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Antimicrobial peptides of the oral cavity.口腔抗菌肽
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Role of peptide hydrophobicity in the mechanism of action of alpha-helical antimicrobial peptides.肽疏水性在α-螺旋抗菌肽作用机制中的作用
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Role of polymorphonuclear leukocyte-derived serine proteinases in defense against Actinobacillus actinomycetemcomitans.多形核白细胞衍生的丝氨酸蛋白酶在抵御伴放线放线杆菌中的作用。
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Peptide antimicrobial agents.肽类抗菌剂。
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The oral cleanliness and periodontal health of UK adults in 1998.1998年英国成年人的口腔清洁状况与牙周健康
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10
Cationic amphipathic peptides, derived from bovine and human lactoferrins, with antimicrobial activity against oral pathogens.源自牛乳铁蛋白和人乳铁蛋白的阳离子两亲性肽，对口腔病原体具有抗菌活性。
FEMS Microbiol Lett. 1999 Oct 15;179(2):217-22. doi: 10.1111/j.1574-6968.1999.tb08730.x.

抗菌肽在牙周健康与疾病中的作用——综述

Role of Antimicrobial Peptides in Periodontal Health and Disease-A Review.

作者信息

Patil Ruchita T, Dhadse Prasad V, Wankhede Anand N, Punse Sanehi D

机构信息

Department of Periodontics, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Higher Education and Research, (Deemed to be University) Sawangi (Meghe), Wardha, Maharashtra, India.

出版信息

J Pharm Bioallied Sci. 2025 May;17(Suppl 1):S172-S174. doi: 10.4103/jpbs.jpbs_1668_24. Epub 2025 Feb 15.

DOI:10.4103/jpbs.jpbs_1668_24
PMID:40511148
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12156665/
Abstract

Periodontitis is an inflammatory condition that results from the interaction between the host immune system and periopathogens, which leads to the development of periodontal attachment loss, periodontal pocket, and resorption of the alveolar bone. With advances in scientific research on antimicrobial peptides (AMPs), they play a crucial role in modulating immune response as well as act as antimicrobials. This review is focused on the role of AMPs in maintaining the periodontal health.

摘要

牙周炎是一种炎症性疾病，由宿主免疫系统与牙周病原体相互作用引起，导致牙周附着丧失、牙周袋形成以及牙槽骨吸收。随着抗菌肽（AMPs）科学研究的进展，它们在调节免疫反应以及作为抗菌剂方面发挥着关键作用。本综述聚焦于抗菌肽在维持牙周健康中的作用。