Wise R A, Wigley F M, Malamet R
Angiology. 1985 Sep;36(9):596-602. doi: 10.1177/000331978503600902.
In order to determine whether subjects with Raynaud's phenomenon have altered digital hemodynamics in the warm basal condition, we characterized the digital pressure-flow relationships in seven subjects with Raynaud's phenomenon and compared the results with age and sex matched control subjects. Digital pressure-flow relationships were measured by the use of a plethysmographic technique during passive elevation of the arm. Normal subjects demonstrated a positive finger systolic pressure at zero flow (48.3 mmHg), indicative of a critical closing pressure, however, the closing pressure was significantly higher in the subjects who had a history of Raynaud's phenomenon (64.7 mmHg, p less than .001). In contrast, there was no significant difference found in the conductance measured as the slope of the pressure-flow relationship. Subjects with Raynaud's phenomenon demonstrated a correlation between finger systolic pressure and critical closing pressure suggesting that these subjects may regulate arterial pressure through a critical closing pressure mechanism.
为了确定患有雷诺现象的受试者在温暖基础状态下是否存在指端血流动力学改变，我们对7名患有雷诺现象的受试者的指端压力-血流关系进行了表征，并将结果与年龄和性别匹配的对照受试者进行了比较。在手臂被动抬高期间，通过使用体积描记技术测量指端压力-血流关系。正常受试者在零流量时显示出正的手指收缩压（48.3 mmHg），这表明存在临界关闭压，然而，有雷诺现象病史的受试者的关闭压明显更高（64.7 mmHg，p小于0.001）。相比之下，以压力-血流关系斜率测量的电导没有发现显著差异。患有雷诺现象的受试者显示出手指收缩压与临界关闭压之间的相关性，这表明这些受试者可能通过临界关闭压机制调节动脉压。
