Salehi Sarmad, Golestani Ali, Rezaei Nazila, Azizpour Yosra, Mirzad Mina, Fotouhi Maryam, Khosravi Sepehr, Tabatabaei-Malazy Ozra
Non-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran; Department of Epidemiology & Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Non-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Public Health. 2025 Sep;246:105798. doi: 10.1016/j.puhe.2025.105798. Epub 2025 Jun 12.
This study aimed to investigate smoking patterns and their relationship with uncontrolled blood pressure in Iranian adults with hypertension.
A cross-sectional study was conducted to explore the research objectives.
This study used data from the 2021 national Stepwise Approach to Chronic Disease Risk Factor Surveillance (STEPS) survey, which employed a clustered sampling technique to recruit Iranian adults aged ≥18 years from urban and rural areas across 31 provinces. Hypertension was defined as a systolic blood pressure (SBP) ≥140 mmHg, diastolic blood pressure (DBP) ≥90 mmHg, a history of hypertension diagnosis or use of antihypertensive medication. Smoking behaviours, including cigarette and hookah use, were assessed using the STEPS questionnaire. Data on sociodemographic variables, physical activity (min/weeks) and comorbidities were also collected. This study used t-tests and chi-square tests, as well as multivariable regression models adjusting for covariates, to examine the relationship between smoking status and blood pressure.
Among 27,874 participants, 8883 with hypertension were included in the analysis. The weighted prevalence of uncontrolled hypertension was 71.25 %. Smoking patterns revealed that 58.75 % were never smokers, 3.47 % were ex-smokers, 12.13 % were current smokers and 25.65 % were passive smokers. Current smokers had a higher prevalence of controlled hypertension (31.43 %) compared to ex-smokers (26.05 %), but the differences were not statistically significant (p = 0.225). Current smokers had 44 % lower odds of being ≥60 years (versus 18-39-year-olds) and were 8.32 times more likely to be male than female. Higher body mass index (BMI) and a higher wealth index were each associated with reduced odds of smoking, whereas alcohol consumption was linked to increased odds. Current smoking was associated with a 0.24 mmHg increase in SBP and a 0.35 mmHg decrease in DBP, but these associations were not statistically significant.
This study revealed a high prevalence of smoking among hypertensive individuals, especially among younger males, those with lower BMI and alcohol users. These findings underscore the need for culturally tailored smoking cessation programmes and longitudinal research to clarify the causal pathways of tobacco use in this high-risk group.
本研究旨在调查伊朗成年高血压患者的吸烟模式及其与血压控制不佳之间的关系。
采用横断面研究来探索研究目标。
本研究使用了2021年全国慢性病危险因素监测逐步调查(STEPS)的数据,该调查采用整群抽样技术,从31个省的城乡地区招募年龄≥18岁的伊朗成年人。高血压定义为收缩压(SBP)≥140 mmHg、舒张压(DBP)≥90 mmHg、有高血压诊断史或使用抗高血压药物。使用STEPS问卷评估吸烟行为,包括香烟和水烟的使用情况。还收集了社会人口统计学变量、身体活动(分钟/周)和合并症的数据。本研究使用t检验和卡方检验,以及调整协变量的多变量回归模型,来检验吸烟状况与血压之间的关系。
在27874名参与者中,8883名高血压患者被纳入分析。未控制高血压的加权患病率为71.25%。吸烟模式显示,58.75%为从不吸烟者,3.47%为曾经吸烟者,12.13%为当前吸烟者,25.65%为被动吸烟者。与曾经吸烟者(26.05%)相比,当前吸烟者的高血压控制患病率更高(31.43%),但差异无统计学意义(p = 0.225)。当前吸烟者60岁及以上(与18 - 39岁者相比)的几率低44%,且男性吸烟的可能性是女性的8.32倍。较高的体重指数(BMI)和较高的财富指数均与吸烟几率降低相关,而饮酒则与吸烟几率增加相关。当前吸烟与SBP升高0.24 mmHg和DBP降低0.35 mmHg相关,但这些关联无统计学意义。
本研究显示高血压患者中吸烟率较高,尤其是在年轻男性、BMI较低者和饮酒者中。这些发现强调需要开展针对文化特点的戒烟项目以及纵向研究,以阐明该高危人群烟草使用的因果途径。