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[极低出生体重儿先天性甲状腺功能减退症的新生儿筛查问题]

[Problems of neonatal screening for hypothyroidism in the very low birth-weight neonate].

作者信息

Eguileor I, Arena J, Aniel A, Rodríguez J L, Galdeano L, Sanjurjo P

出版信息

An Esp Pediatr. 1985 Jun;22(8):551-5.

PMID:4051339
Abstract

21,013 newborns were screened on the first year of a neonatal screening program on congenital hypothyroidism in the Basque Community. The evaluation of the results showed some points of interest. One of them, would be the high analytical retesting rate needed in the screening of very low-birth weight children. The rate decreased with increasing birth-weight. Forty per cent of the children with a birth-weight lower than 1,000 gr needed retesting. The rate decreased to 7.7% at birth-weights between 1,001 and 1,500 gr, to 2% at birth weights between 1,501 and 2,500 gr and only to 0,42% at birth-weights higher than 2,501 gr. The consequences of these results are discussed.

摘要

在巴斯克地区开展的先天性甲状腺功能减退症新生儿筛查项目的第一年,对21,013名新生儿进行了筛查。对结果的评估显示出一些值得关注的点。其中之一是对极低出生体重儿进行筛查时需要较高的分析复检率。该比率随着出生体重的增加而降低。出生体重低于1000克的儿童中有40%需要复检。出生体重在1001至1500克之间时,该比率降至7.7%;出生体重在1501至2500克之间时,降至2%;而出生体重高于2501克时,仅降至0.42%。本文讨论了这些结果的影响。

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