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[Mutants of Escherichia coli deficient in 4-thiouridine in which growth is insensitive to illumination at 365 nm].

作者信息

Thomas G, Favre A

出版信息

C R Acad Hebd Seances Acad Sci D. 1977 Apr 4;284(14):1345-7.

PMID:405149
Abstract

Thirteen different mutants of E coli K12 selected for a reduced near ultra-violet induced growth delay have been isolated. The t-RNAs extracted from these clones have all a depressed content of 4-thiouridine. One of these mutants, called Nop has an almost negligible growth delay and completely lacks 4-thiouridine in its t-RNAs. Thus we provide genetic proofs that 4-thiouridine is the chromophore for growth delay.

摘要

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