Guo Qi, Lu Liqin, Wen Jiansen, Zhuang Guoxin
Department of Critical Care Medicine, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, 1st Shuaifuyuan, Dongcheng District, Beijing, 100730, China.
Department of Forensic Science, Fujian Police College, Fuzhou, 350007, China.
J Fluoresc. 2025 Jun 14. doi: 10.1007/s10895-025-04397-6.
Fingerprints are among the most commonly encountered forms of forensic evidence. However, current databases require relatively complete fingerprints to extract sufficient level 2 features for individual identification, thereby limiting the recognition of partial latent fingerprints (LFPs) collected from crime scenes. Therefore, visualizing level 3 features of LFPs (such as width, spacing, and distribution of ridge and pore) is of critical importance. In response to this challenge, this study developed a near-infrared AIE fluorescent probe (D-TPA-A-TXO) with a D-A structure. In ethanol/water binary solvents, D-TPA-A-TXO enabled rapid and distinct in-situ visualization of level 3 LFPs features across various substrates. Owing to its lipophilic nature, D-TPA-A-TXO rapidly dissolved from the solution into the lipid components of LFPs and continuously aggregated. Through the aggregation-induced emission (AIE) effect, high-resolution images of level 3 LFPs features could be directly captured by a standard camera. This advancement provides crucial technical support for enhancing the matching capability of partial fingerprints in future criminal investigations.
指纹是最常见的法医证据形式之一。然而，当前的数据库需要相对完整的指纹来提取足够的二级特征以进行个体识别，从而限制了对从犯罪现场收集的部分潜在指纹（LFPs）的识别。因此，可视化潜在指纹的三级特征（如纹路、间距以及纹路和毛孔的分布）至关重要。针对这一挑战，本研究开发了一种具有D-A结构的近红外AIE荧光探针（D-TPA-A-TXO）。在乙醇/水二元溶剂中，D-TPA-A-TXO能够在各种基材上快速、清晰地原位可视化潜在指纹的三级特征。由于其亲脂性，D-TPA-A-TXO从溶液中迅速溶解到潜在指纹的脂质成分中并持续聚集。通过聚集诱导发光（AIE）效应，潜在指纹的三级特征的高分辨率图像可以用标准相机直接捕捉。这一进展为在未来刑事调查中提高部分指纹的匹配能力提供了关键的技术支持。
