Berzolla Emily, Chen Larry, Gosnell Griffith G, Mercer Nathaniel, Seidenberg Julian, Kaplan Daniel J, Youm Thomas
Department of Orthopedic Surgery, NYU Langone Orthopedic Center, New York, New York, USA.
Am J Sports Med. 2025 Jul;53(9):2217-2222. doi: 10.1177/03635465251344594. Epub 2025 Jun 14.
The minimal clinically important difference (MCID), Patient Acceptable Symptom State (PASS), and substantial clinical benefit (SCB) are valuable clinical thresholds used to provide clinical relevance to patient outcome scores. In hip arthroscopy (HA) for femoroacetabular impingement (FAI) syndrome, these values have been defined for the short- and midterm postoperative period, but meaningful long-term thresholds have not been established.
To define the MCID, PASS, and SCB for the modified Harris Hip Score (mHHS) and Nonarthritic Hip Score (NAHS) at a minimum follow-up of 10 years for patients who underwent HA for FAI syndrome.
Case series; Level of evidence, 4.
A retrospective cohort study including all patients who underwent primary HA for FAI with a single surgeon from February 2010 to December 2013 was performed. Patient outcomes were assessed with an anchor question, mHHS, and NAHS at baseline and at 1, 5, and 10 years of follow-up. MCID was calculated using the distribution-based method at all time points, using 0.5 standard deviations as the threshold. The anchor-based MCID, PASS, and SCB were calculated at 10 years using thresholds representing the optimal cutoff on a receiver operating characteristic curve. Correlations between baseline characteristics and achievement of the MCID, PASS, and SCB were assessed with binomial logistic regressions.
The 154 patients included in the study had a mean age of 38.8 ± 13.0 years, a mean body mass index of 24.6 ± 3.9 kg/m, and 63.6% were female. The distribution-based MCID values for 1-year, 5-year, and 10-year scores were 7.8, 8.3, and 9.5 for mHHS and 9.5, 10.4, and 10.2 for NAHS, respectively. The anchor-based MCID was 20.3 for mHHS and 24.4 for NAHS. The PASS was 81.9 for mHHS and 83.1 for NAHS. The SCB values were 34.0 and 41.9 for mHHS and NAHS, respectively. Increased body mass index was associated with decreased achievement of SCB for mHHS ( = .03) and NAHS ( = .04), as well as NAHS PASS ( = .01) and anchor-based MCID ( = .01).
The establishment of the MCID, SCB, and PASS for the NAHS and mHHS provides a valuable clinical context for improvements in outcome scores after HA. Anchor-based calculations were consistently higher than distribution-based calculations.
最小临床重要差异(MCID)、患者可接受症状状态(PASS)和显著临床获益(SCB)是用于使患者结局评分具有临床相关性的重要临床阈值。在针对股骨髋臼撞击(FAI)综合征的髋关节镜检查(HA)中,这些值已针对术后短期和中期进行了定义,但尚未确立有意义的长期阈值。
为接受HA治疗FAI综合征的患者在至少10年的随访中定义改良Harris髋关节评分(mHHS)和非关节炎髋关节评分(NAHS)的MCID、PASS和SCB。
病例系列;证据等级,4级。
进行了一项回顾性队列研究,纳入了2010年2月至2013年12月由单一外科医生进行初次HA治疗FAI的所有患者。在基线以及随访1年、5年和10年时,使用一个锚定问题、mHHS和NAHS对患者结局进行评估。在所有时间点使用基于分布的方法计算MCID,以0.5个标准差作为阈值。在10年时使用代表受试者操作特征曲线上最佳截断值的阈值计算基于锚定的MCID、PASS和SCB。使用二项逻辑回归评估基线特征与达到MCID、PASS和SCB之间的相关性。
纳入研究的154例患者的平均年龄为38.8±13.0岁,平均体重指数为24.6±3.9kg/m²,63.6%为女性。mHHS在1年、5年和10年评分的基于分布 的MCID值分别为7.8、8.3和9.5,NAHS分别为9.5、10.4和10.2。mHHS基于锚定的MCID为20.3,NAHS为24.4。mHHS的PASS为81.9,NAHS为83.1。mHHS和NAHS的SCB值分别为34.0和41.9。体重指数增加与mHHS(P = 0.03)和NAHS(P = 0.04)的SCB达成率降低以及NAHS的PASS(P = 0.01)和基于锚定的MCID(P = 0.01)降低相关。
NAHS和mHHS的MCID、SCB和PASS的确定为HA后结局评分的改善提供了有价值的临床背景。基于锚定的计算结果始终高于基于分布的计算结果。