Gogina I F
Arkh Anat Gistol Embriol. 1985 Jun;88(6):48-52.
The ultrastructure of the bulbar conjunctiva bioptates have been studied in 12 persons suffering from lead intoxication (saturnism), 2-from tetraethyl-lead (TEL) intoxication and 3-are practically healthy persons; they make the control group. In all the patients manifested disturbances in the microcirculatory bed of the bulbar conjunctiva are revealed, the general character being identical at saturnism and TEL-intoxication. The main changes are observed in the wall of the blood microvessels: destruction of the endothelial lining up to revealing the basal membrane with adhesion of the blood formed elements and their diapedesis. This results in disorders of vascular permeability, in edema of the perivascular space and in appearance of cells and cellular detritus in it. An essential role in morphogenesis of the vascular disturbances produced by intoxication play certain rheological imparements: sludge-syndrome and microthrombosis. They produce certain distrophic changes.
对12例铅中毒（铅中毒症）患者、2例四乙基铅（TEL）中毒患者和3例实际健康者（作为对照组）的球结膜活检组织超微结构进行了研究。在所有患者中均发现球结膜微循环床存在紊乱，铅中毒症和TEL中毒时的总体特征相同。主要变化见于血液微血管壁：内皮衬里破坏直至基底膜暴露，伴有血液有形成分黏附及其渗出。这导致血管通透性紊乱、血管周围间隙水肿以及其中出现细胞和细胞碎屑。中毒所致血管紊乱的形态发生中，某些流变学障碍（淤滞综合征和微血栓形成）起重要作用。它们会产生一定的营养不良性变化。
