Rottenberg V I, Timofeev Iu M
Arkh Patol. 1985;47(6):54-61.
Seventy-four carcinomas of the anal canal (4,9% of the total number of rectum carcinoma for 1952-1982) were studied, including 45 squamous-cell, 23 adenogenic and 6 undifferentiated carcinomas. Adenogenic carcinomas originated from the rectum mucous membrane over the serrated line; as distinct from carcinomas of other parts of the rectum the mucus-forming and poorly differentiated tumours were predominant among them. Squamous-cell carcinomas originated from the squamous epithelium of the lower part of the anal canal, from the transitional area and from the rectum mucous membrane over the serrated line. They were characterized by peculiarity of their histological structure: they included 11 basaloid carcinomas, 6 carcinomas resembling transitional-cell carcinoma of the urinary bladder, 12 carcinomas resembling carcinoma of the uterine cervix. The problems of the terminology, histogenesis, clinical course of the anal canal carcinoma are discussed.
对74例肛管癌(占1952 - 1982年直肠癌总数的4.9%)进行了研究,其中包括45例鳞状细胞癌、23例腺源性癌和6例未分化癌。腺源性癌起源于锯齿线以上的直肠黏膜;与直肠其他部位的癌不同,其中黏液形成性和低分化肿瘤占主导。鳞状细胞癌起源于肛管下部的鳞状上皮、移行区以及锯齿线以上的直肠黏膜。它们具有独特的组织结构特征:包括11例基底样癌、6例类似膀胱移行细胞癌的癌、12例类似子宫颈癌的癌。文中讨论了肛管癌的术语、组织发生、临床病程等问题。