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[人工循环后贫血中的红细胞形态(基于扫描电子显微镜数据)]

[Erythrocyte morphology in anemia after artificial circulation (based on scanning electron microscopic data)].

作者信息

Krymskiĭ L D, Mozhina A A, Tereshchenko S N

出版信息

Arkh Patol. 1985;47(7):46-54.

PMID:4051815
Abstract

Erythrocyte stereo-ultrastructure of 58 patients operated under the conditions of extracorporeal circulation was studied by scanning electron microscopy. It is established that after the operation with extracorporeal circulation the hemoglobin level is always decreasing, 3 mg% on the average; hemoglobin decrease up to 10 mg% and less was considered as anemia, this occurring according to the approximate calculations, in 10-11% of cases. The causes of anemia in an early postoperative period are as follows: mechanical trauma of erythrocytes in the system of extracorporeal circulation; disturbance of the osmotic balance; alteration of the erythrocyte membrane plasticity due to the change of its enzyme-lipid component. Anemia in the late postoperative period is due to the purulent inflammatory processes. Morphological substrate of anemia is represented by the iron-deficient, target-like, two-pit erythrocytes, spherocytes, lacerated erythrocytes and other forms.

摘要

采用扫描电子显微镜对58例在体外循环条件下接受手术的患者的红细胞立体超微结构进行了研究。结果表明,体外循环手术后血红蛋白水平总是下降,平均下降3mg%;血红蛋白下降至10mg%及以下被视为贫血,据大致计算,这种情况发生在10 - 11%的病例中。术后早期贫血的原因如下:体外循环系统中红细胞的机械损伤;渗透平衡紊乱;由于酶 - 脂质成分的变化导致红细胞膜可塑性改变。术后晚期贫血是由脓性炎症过程引起的。贫血的形态学基础表现为缺铁性、靶形、双凹红细胞、球形红细胞、破碎红细胞及其他形式。

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