Ramón-García Santiago
Research and Development Agency of Aragón Foundation (Fundación ARAID), Zaragoza, Spain; Department of Microbiology, Pediatrics, Radiology and Public Health, Faculty of Medicine, University of Zaragoza, Spain.
Trends Biotechnol. 2025 Jul;43(7):1523-1524. doi: 10.1016/j.tibtech.2025.06.004. Epub 2025 Jun 14.
Antimicrobial resistance (AMR) is a global public health concern that is becoming a 'silent' pandemic. Novel treatment strategies are urgently needed to counteract this growing threat. To this end, Ageitos et al. leverage the natural antibacterial armamentarium of frogs to develop novel optimized synthetic peptides selective against Gram-negative pathogens.
抗菌耐药性（AMR）是一个全球公共卫生问题，正在成为一场“无声”的大流行。迫切需要新的治疗策略来应对这一日益严重的威胁。为此，阿盖托斯等人利用青蛙的天然抗菌武器库，开发出对革兰氏阴性病原体具有选择性的新型优化合成肽。
