The effect of prostaglandins on the isolated internal muscles of the mammalian eye, including man.

The effects of PG's on the isolated intraocular muscles were determined in cat, rabbit, monkey and man, as well as their interactions with cholinergic agents and with catecholamines; the effects of PG antagonists; the effects of PG synthetase inhibitors; and the effects of cholinergic and adrenergic blockade and depletion. It is speculated that PG's may be involved in the regulation of the pupil and accommodation.