Yang Xiaochen, Liu Lanping, Li Yirun, Feng Ling, Yang Tao, Gao Yinqiu
Department of Pain Treatment, Guang'anmen Hospital of China Academy of Chinese Medical Sciences, Beijing 100053, China.
Department of Acupuncture and Moxibustion, Guang'anmen Hospital of China Academy of Chinese Medical Sciences, Beijing 100053, China.
Zhongguo Zhen Jiu. 2025 Jun 12;45(6):728-734. doi: 10.13703/j.0255-2930.20240621-k0005. Epub 2024 Dec 18.
To investigate the clinical effect on functional dyspepsia differentiated as liver-stomach disharmony treated with acupoint application of Chinese herbal medicine and wax therapy on the basis of Professor 's theory, "regulating movement".
A total of 120 patients with functional dyspepsia of liver-stomach disharmony were randomly assigned to a combined therapy group (30 cases, 1 case dropped out), an acupoint application group (30 cases, 1 case dropped out), a wax therapy group (30 cases, 1 case dropped out) and a basic therapy group (30 cases, 2 cases dropped out). In the basic therapy group, omeprazole magnesium enteric-coated tablets were administered orally, 20 mg each time, once daily. Besides the treatment as the basic therapy group, the Chinese herbal acupoint application was used at Zhongwan (CV12) and Shenque (CV8) in the acupoint application group, and remained for 4 h in each intervention; and in the wax therapy group, wax therapy was delivered at the sites of Zhongwan (CV12) and Shenque (CV8) of the abdominal region and remained for 20 min in each intervention; and in the combined therapy group, the acupoint application was combined with wax therapy, administered once every other day or every two days, 3 times weekly. The duration of treatment was 4 weeks in the four groups. Before and after treatment, the score of main symptoms, the score of 36-item short-form health survey (SF-36) and the score of liver-stomach disharmony pattern were observed; and the clinical effect was evaluated in the four groups.
After treatment, regarding main symptoms and liver-stomach disharmony pattern, the score of every item was lower than that before treatment in the 4 groups (<0.01). The score for each dimension in SF-36 was higher than that before treatment in the combined therapy group and the acupoint application group (<0.01, <0.05). In the wax therapy group, the scores for physiological activities, bodily pain, general health, vitality, social activities and mental health in SF-36 were higher than those before treatment (<0.01, <0.05). In the basic therapy group, the scores for physiological performance, bodily pain, general health and mental health in SF-36 were higher than those before treatment (<0.05, <0.01). After treatment, in the combined therapy group, the score for gastric distension and discomforts was lower than those of the basic therapy group and the wax therapy group (<0.01), and the scores for gastric fullness in the morning, pain in the upper abdominal region and burning sensation in the upper abdominal region, as well as the score for liver-stomach disharmony pattern were lower than those in the rest 3 groups (<0.01, <0.05). In the combined therapy group, the scores for physiological activities, physiological performance, and bodily pain were higher than those of the basic therapy group (<0.01, <0.05), the scores for physiological activities and bodily pain were higher when compared with those in the acupoint application group (<0.01, <0.05) and the scores for physiological activities and vitality were higher when compared with those in the wax therapy group (<0.05). After treatment, the score for each item of main symptoms, the score for liver-stomach disharmony pattern in the acupoint application group, and the score for liver-stomach disharmony pattern in the wax therapy group were all lower in comparison with those in the basic therapy group (<0.01, <0.05). The total effective rates was 93.3% (28/30), 73.3% (22/30), 66.7% (20/30) and 50.0% (15/30) in the combined therapy group, the acupoint application group, the wax therapy group and the basic therapy group, respectively; and the total effective rate in the combined therapy group was superior to the other 3 groups (<0.01); the total effective rates in the acupoint application group and the wax therapy group were higher than that in the basic therapy group (<0.01).
The combination of acupoint application with Chinese herbal medicine and wax therapy, based on Professor 's theory of "regulating movement", can effectively treat functional dyspepsia, alleviate main symptoms and improve the quality of life in the patients.
基于某教授“调畅气机”理论，探讨中药穴位贴敷联合蜡疗治疗肝胃不和型功能性消化不良的临床疗效。
将120例肝胃不和型功能性消化不良患者随机分为联合治疗组（30例，脱落1例）、穴位贴敷组（30例，脱落1例）、蜡疗组（30例，脱落1例）和基础治疗组（30例，脱落2例）。基础治疗组口服奥美拉唑镁肠溶片，每次20mg，每日1次。穴位贴敷组除基础治疗外，于中脘（CV12）、神阙（CV8）行中药穴位贴敷，每次干预保留4小时；蜡疗组于腹部中脘（CV12）、神阙（CV8）部位行蜡疗，每次干预保留20分钟；联合治疗组采用穴位贴敷与蜡疗相结合的方法，隔日或每两日治疗1次，每周3次。四组治疗疗程均为4周。观察四组治疗前后主要症状积分、36条目简明健康调查问卷（SF-36）积分及肝胃不和证积分，并评价临床疗效。
治疗后，四组主要症状及肝胃不和证各条目积分均低于治疗前（<0.01）。联合治疗组和穴位贴敷组SF-36各维度积分高于治疗前（<0.01，<0.05）。蜡疗组SF-36中生理功能、躯体疼痛、总体健康、活力、社会功能及精神健康积分高于治疗前（<0.01，<0.05）。基础治疗组SF-36中生理机能、躯体疼痛、总体健康及精神健康积分高于治疗前（<0.05，<0.01）。治疗后，联合治疗组胃脘胀满不适积分低于基础治疗组和蜡疗组（<0.01），早饱、上腹部疼痛、上腹部烧灼感积分及肝胃不和证积分低于其余3组（<0.01，<0.05）。联合治疗组生理功能、生理机能、躯体疼痛积分高于基础治疗组（<0.01，<0.05），生理功能、躯体疼痛积分高于穴位贴敷组（<0.01，<0.05），生理功能、活力积分高于蜡疗组（<0.05）。治疗后，穴位贴敷组和蜡疗组主要症状各条目积分、肝胃不和证积分均低于基础治疗组（<0.01，<0.05）。联合治疗组、穴位贴敷组、蜡疗组和基础治疗组总有效率分别为93.3%（28/30）、73.3%（22/30）、66.7%（20/30）、50.0%（15/30）；联合治疗组总有效率优于其余3组（<0.01）；穴位贴敷组和蜡疗组总有效率高于基础治疗组（<0.01）。
基于某教授“调畅气机”理论，中药穴位贴敷联合蜡疗能有效治疗功能性消化不良，缓解主要症状，提高患者生活质量。
