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一种用于使血管缓慢渐进性狭窄的新装置。

A new device for slow progressive narrowing of vessels.

作者信息

Lange P E, Sievers H H, Nürnberg J H, Engler K, Pilarczyk J, Onnasch D G, Bernhard A, Heintzen P H

出版信息

Basic Res Cardiol. 1985 Jul-Aug;80(4):430-5. doi: 10.1007/BF01908187.

DOI:10.1007/BF01908187
PMID:4051945
Abstract

The purpose of this work was to develop a device which allows slow progressive banding of a great artery in infants within 4 to 5 weeks. Employed was the hygroscopic casein ameroid. When brought in contact with fluids, an ameroid cylinder expands characteristically. An early phase of fast expansion proceeds gradually to a phase of slow growth. Size, shape, and encasement of ameroid as well as temperature and type of surrounding fluid modify but do not alter the typical pattern of expansion. The developed constrictor (weight: 5.8 kg, length: 18 mm, diameter: 12 mm) includes a stainless steel socket containing an ameroid cylinder (length: 8.5 mm, diameter: 8 mm). The expanding ameroid pushes a piston with a concave extension (makrolon) a maximum of 2 mm against the artery, which is fixed to the metal housing by a teflon band (width: 4 mm, thickness: 0.5 mm). The band runs in 2 fitting grooves on the metal housing to which it is fixed by a metal ring with a precisely manufactured internal thread allowing exact tightening and loosening of the band around the artery. Utilization of inert materials like teflon, makrolon, and stainless steel warrants experimental and possibly clinical application of the developed small constrictor.

摘要

这项工作的目的是研发一种装置,该装置能够在4至5周内对婴儿的大动脉进行缓慢渐进性束带结扎。使用的是吸湿酪蛋白类环。当与液体接触时,类环圆柱体具有典型的膨胀现象。早期的快速膨胀阶段会逐渐过渡到缓慢生长阶段。类环的尺寸、形状、封装以及周围液体的温度和类型会对膨胀的典型模式产生影响,但不会改变其模式。所研发的束带结扎器(重量:5.8千克,长度:18毫米,直径:12毫米)包括一个不锈钢套管,套管内装有一个类环圆柱体(长度:8.5毫米,直径:8毫米)。膨胀的类环将带有凹形延伸部分(聚碳酸酯)的活塞向动脉方向最多推2毫米,动脉通过一个聚四氟乙烯带(宽度:4毫米,厚度:0.5毫米)固定在金属外壳上。该带在金属外壳上的2个适配凹槽中运行,并通过一个带有精确制造的内螺纹的金属环固定在外壳上,从而能够精确地收紧和松开围绕动脉的束带。使用聚四氟乙烯、聚碳酸酯和不锈钢等惰性材料保证了所研发的小型束带结扎器可用于实验以及可能的临床应用。

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Response of the right ventricle to progressive pressure loading in pigs.
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本文引用的文献

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Experimental gradual coronary artery constriction by ameroid constrictors.使用阿梅罗氏缩窄环进行实验性冠状动脉渐进性缩窄。
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