Akasaka Toshihiko, Takami Aiko, Higuchi Ryo, Ogura Kazuyoshi, Nasu Hiroshi, Yamamoto Kazuhiro
Department of Cardiology, Tottori Prefectural Hospital, Tottori, Japan.
Department of Cardiovascular Medicine, and Endocrinology and Metabolism, Faculty of Medicine, Tottori University, Yonago, Japan.
J Cardiol Cases. 2025 Feb 25;31(6):166-169. doi: 10.1016/j.jccase.2025.02.005. eCollection 2025 Jun.
A patient with ulcerated skin lesions of unknown etiology on his left leg underwent pacemaker implantation for atrioventricular block caused by cardiac sarcoidosis (CS). After initiation of corticosteroid for CS, his skin lesions improved. The lesions were diagnosed as pyoderma gangrenosum (PG) from the findings of a skin biopsy and the reaction to corticosteroid. PG causes skin necrosis associated with immune system disorders after slight stimulation. Although we worried about wound healing after pacemaker implantation, the wound healed well under the corticosteroid treatment. This is the first report of successful pacemaker implantation in a patient with both PG and CS.
Conventional transvenous pacemakers can be implanted for pyoderma gangrenosum patients by early initiation of corticosteroid.
一名左腿患有病因不明的溃疡性皮肤病变的患者因心脏结节病(CS)导致的房室传导阻滞接受了起搏器植入术。在开始使用皮质类固醇治疗CS后,他的皮肤病变有所改善。根据皮肤活检结果和对皮质类固醇的反应,病变被诊断为坏疽性脓皮病(PG)。PG在轻微刺激后会导致与免疫系统紊乱相关的皮肤坏死。尽管我们担心起搏器植入术后的伤口愈合情况,但在皮质类固醇治疗下伤口愈合良好。这是首例成功为同时患有PG和CS的患者植入起搏器的报告。
通过早期使用皮质类固醇,可以为坏疽性脓皮病患者植入传统的经静脉起搏器。