Tabibi Ali, Zabihi Mohammad Sajjad, Najarian Mahyar, Dadpour Mehdi
Shahid Labbafinejad Medical Center, The Center of Excellence in Urology, Urology and Nephrology Research center, Research Institute of Urology and Nephrology, Shahid Beheshti University of medical Sciences, Tehran, Iran.
Urol Case Rep. 2025 May 27;61:103080. doi: 10.1016/j.eucr.2025.103080. eCollection 2025 Jul.
This case report presents a 61-year-old male patient diagnosed with high-risk prostate cancer who underwent hormone therapy and radiotherapy. Three years after beginning treatment, rising prostate-specific antigen (PSA) levels led to a PET CT scan, which identified isolated metastases in the left testicle. The patient then underwent a radical orchiectomy. One-year follow up revealed undetectable PSA and no evidence of any metastases. The significance of this case lies in the uncommon occurrence of testicular metastasis from prostate cancer, particularly when presenting in isolation after a prolonged period following hormone therapy and radiotherapy.
本病例报告介绍了一名61岁的男性患者，他被诊断为高危前列腺癌，接受了激素治疗和放射治疗。治疗开始三年后，前列腺特异性抗原（PSA）水平升高，于是进行了PET CT扫描，结果发现左侧睾丸有孤立性转移灶。该患者随后接受了根治性睾丸切除术。一年的随访显示PSA检测不到，且无任何转移迹象。本病例的意义在于前列腺癌发生睾丸转移的情况不常见，尤其是在激素治疗和放射治疗后的较长时间后单独出现。
