两名患有Ia型糖原贮积病和先兆子痫患者的胎盘病理学
Placenta Pathologies in Two Patients With Glycogen Storage Disease Type Ia and Preeclampsia.
作者信息
Laufs V, Hasenburg A, Busch M A, Lang F, Macchiella D, Mildenberger E, Seidmann L, Hennermann J B
机构信息
Clinic for Obstetrics and Women's Health University Medical Center of the Johannes Gutenberg-University Mainz Mainz Germany.
Division of Neonatology Center for Pediatric and Adolescent Medicine, University Medical Center of the Johannes Gutenberg-University Mainz Mainz Germany.
出版信息
JIMD Rep. 2025 Jun 12;66(4):e70025. doi: 10.1002/jmd2.70025. eCollection 2025 Jul.
Little is known about pregnancies and placental changes in women with glycogen storage disease type Ia (GSD Ia). We report on two primipara with GSD Ia who both developed preeclampsia and whose newborns were small for gestational age. Both placentas showed sonomorphological and macroscopical abnormalities. Disease-specific histological features could not be identified, which should prompt further research.
关于Ia型糖原贮积病（GSD Ia）女性的妊娠情况和胎盘变化，人们所知甚少。我们报告了两名患有GSD Ia的初产妇，她们均发生了先兆子痫，且其新生儿均为小于胎龄儿。两个胎盘均显示出超声形态学和宏观异常。未发现疾病特异性组织学特征，这应促使进一步研究。
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