Lobb R R, Strydom D J, Fett J W
Biochem Biophys Res Commun. 1985 Sep 16;131(2):586-92. doi: 10.1016/0006-291x(85)91277-x.
Two growth factors have been purified to homogeneity from human brain using heparin affinity chromatography. They have apparent molecular weights of 17 Kd and 18 Kd. Their amino acid compositions differ, but are similar to those of the two heparin-binding growth factors present in bovine neural tissue. These results suggest that the heparin-binding growth factors in neural tissue can be grouped into two distinct classes.
利用肝素亲和层析法已从人脑中纯化出两种生长因子，使其达到均一状态。它们的表观分子量分别为17千道尔顿和18千道尔顿。它们的氨基酸组成不同，但与牛神经组织中存在的两种肝素结合生长因子的氨基酸组成相似。这些结果表明，神经组织中的肝素结合生长因子可分为两个不同的类别。
