Kulkarni Arvind G, Patil Shankargouda, Agrawal Aniruddh, Chodavadiya Sunil, Kumar Priyambada
Mumbai Spine Scoliosis and Disc Replacement Centre, Bombay Hospital and Medical Research Centre, Marine Lines, Mumbai, Maharashtra, India.
Department of Spine Surgery, Bombay Hospital Institute of Medical Sciences, Mumbai, Maharashtra, India.
J Orthop Case Rep. 2025 Jun;15(6):185-189. doi: 10.13107/jocr.2025.v15.i06.5710.
Occurrence of a focal lytic lesion which is "hot" on positron emission tomography (PET) scan is presumed to be neoplastic until proven otherwise. Focal osteonecrosis of vertebral body (VB) without collapse is a rare entity with sparse literature available.
A focal osteolytic lesion in a patient with a history of breast carcinoma, in remission, thought to be metastatic lesion on magnetic resonance imaging and PET-computed tomography (CT), with an inconclusive CT-guided biopsy, was found to be osteonecrosis on histopathology of aggregates of tissue obtained from the T9 VB during open surgery.
Osteonecrosis without a VB collapse is a rare diagnosis, but should be considered a differential when examining suspected metastatic lesions in VB.
在正电子发射断层扫描(PET)上表现为“热”的局灶性溶骨性病变,在未得到其他证明之前,一般认为是肿瘤性病变。椎体(VB)无塌陷的局灶性骨坏死是一种罕见疾病,相关文献较少。
一名缓解期乳腺癌患者出现局灶性溶骨性病变,在磁共振成像和PET计算机断层扫描(CT)上被认为是转移瘤,CT引导下活检结果不明确,在开放手术中从T9椎体获取的组织团块病理检查发现为骨坏死。
无椎体塌陷的骨坏死是一种罕见诊断,但在检查疑似椎体转移瘤时应考虑作为鉴别诊断。