Wang Juan, Bai Lu, Xu Yuchen, Zheng Xinhang, Shan Wenfeng, Shi Xuetao, Ma Shoucai, Fan Jiangbo
Shanghai Collaborative Innovation Center of Agri-Seeds, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China.
Xianghu Laboratory, Hangzhou, China.
Stress Biol. 2025 Jun 16;5(1):43. doi: 10.1007/s44154-025-00219-8.
Receptor-like cytoplasmic kinases (RLCKs) function as a central player in plant receptor kinases-mediated signaling, which regulate various aspects of plant immunity and growth. RLCKs receive signals from pattern recognition receptors (PRRs) to activate pattern-triggered immunity (PTI), including reactive oxygen species (ROS) production, Ca influx, mitogen-activated protein kinase (MAPK) cascades, cellulose synthesis, phosphatidic acid (PA) production, hormone synthesis and signaling, and transcriptional remodeling. Besides, RLCK also participate in effector-triggered immunity (ETI) and the interplay between ETI and PTI. Increasing evidences show that much more RLCKs are involved in plant immune responses and form an intertwined signaling network. This review summarizes the recent findings about RLCKs-mediated signaling in plant immune responses and emphasizes signal convergence and divergence involved which provides new insights into the RLCKs signaling network in diverse biological processes.
类受体细胞质激酶（RLCKs）在植物受体激酶介导的信号传导中起核心作用，该信号传导调节植物免疫和生长的各个方面。RLCKs从模式识别受体（PRRs）接收信号以激活模式触发的免疫（PTI），包括活性氧（ROS）产生、钙离子内流、丝裂原活化蛋白激酶（MAPK）级联反应、纤维素合成、磷脂酸（PA）产生、激素合成和信号传导以及转录重塑。此外，RLCKs还参与效应子触发的免疫（ETI）以及ETI和PTI之间的相互作用。越来越多的证据表明，更多的RLCKs参与植物免疫反应并形成一个相互交织的信号网络。本综述总结了关于RLCKs介导的植物免疫反应信号传导的最新发现，并强调了其中涉及的信号汇聚和发散，这为不同生物学过程中的RLCKs信号网络提供了新的见解。
