Preising Stephanie E, Heck Michelle Lynn
Plant Pathology and Plant Microbe Biology Section, Cornell University School of Integrative Plant Science, Ithaca, New York, USA.
Emerging Pests and Pathogens Research Unit, Robert W. Holley Center for Agriculture and Health, United States Department of Agriculture Agricultural Research Service, Ithaca, New York, USA; email:
Annu Rev Virol. 2025 Sep;12(1):59-77. doi: 10.1146/annurev-virology-092623-103226. Epub 2025 Jun 16.
The aphid holobiont includes the aphid host and aphid-associated microorganisms, including pathogenic plant viruses. The polerovirus potato leafroll virus (PLRV) is transmitted exclusively by aphids and is one of the most economically significant viruses infecting potatoes. In potato plants, PLRV infection results in stunting, leaf rolling, and net necrosis on tubers. PLRV threatens global potato cultivation, especially in regions where vector management options are limited. In this review, we describe the effect of PLRV on the aphid holobiont and highlight studies of the evolutionary and mechanistic ways in which PLRV influences the aphid holobiont during plant infection. We explore ideas to address the pressing need for aphid and PLRV management strategies by targeting interactions within the holobiont. Approaching PLRV-aphid interactions research through the lens of the holobiont allows a systems-level analysis of host, plant, and microbial effects that influence virus transmission. In turn, this knowledge can be leveraged to develop new virus management strategies.
蚜虫共生体包括蚜虫宿主以及与蚜虫相关的微生物，其中包括致病植物病毒。马铃薯卷叶病毒（PLRV）属于马铃薯卷叶病毒属病毒，只能通过蚜虫传播，是感染马铃薯的最具经济重要性的病毒之一。在马铃薯植株中，PLRV感染会导致植株矮化、叶片卷曲以及块茎出现网状坏死。PLRV威胁着全球马铃薯种植，尤其是在媒介管理选择有限的地区。在本综述中，我们描述了PLRV对蚜虫共生体的影响，并重点介绍了关于PLRV在植物感染期间影响蚜虫共生体的进化和机制方式的研究。我们探讨了通过针对共生体内的相互作用来满足对蚜虫和PLRV管理策略迫切需求的思路。从共生体的角度研究PLRV与蚜虫的相互作用，可以对影响病毒传播的宿主、植物和微生物效应进行系统层面的分析。反过来，这些知识可用于制定新的病毒管理策略。
