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松果体恶性肿瘤合并遗传性视网膜母细胞瘤。

Pineal malignant neoplasm in association with hereditary retinoblastoma.

作者信息

Stannard C, Knight B K, Sealy R

出版信息

Br J Ophthalmol. 1985 Oct;69(10):749-53. doi: 10.1136/bjo.69.10.749.

DOI:10.1136/bjo.69.10.749
PMID:4052360
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1040732/
Abstract

A patient with unilateral hereditary retinoblastoma who was successfully treated at the age of 7 weeks developed a tumour in the pineal region two and a half years later. The initial response to radiation treatment of the latter lesion was not maintained. Subsequent necropsy findings are described. Clinically and pathologically this case represents an example of the recently described trilateral retinoblastoma. The response to treatment after early recognition was disappointing.

摘要

一名单侧遗传性视网膜母细胞瘤患者在7周龄时成功接受治疗,两年半后松果体区出现肿瘤。对后一病变的放射治疗初始反应未能维持。描述了随后的尸检结果。从临床和病理角度来看,该病例代表了最近描述的 trilateral retinoblastoma 的一个实例。早期诊断后的治疗反应令人失望。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6955/1040732/7691ab17cd23/brjopthal00142-0035-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6955/1040732/78234d2bb012/brjopthal00142-0034-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6955/1040732/481fe0b327d7/brjopthal00142-0034-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6955/1040732/00781d312e14/brjopthal00142-0034-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6955/1040732/7691ab17cd23/brjopthal00142-0035-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6955/1040732/78234d2bb012/brjopthal00142-0034-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6955/1040732/481fe0b327d7/brjopthal00142-0034-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6955/1040732/00781d312e14/brjopthal00142-0034-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6955/1040732/7691ab17cd23/brjopthal00142-0035-a.jpg

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1
Pineal malignant neoplasm in association with hereditary retinoblastoma.松果体恶性肿瘤合并遗传性视网膜母细胞瘤。
Br J Ophthalmol. 1985 Oct;69(10):749-53. doi: 10.1136/bjo.69.10.749.
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引用本文的文献

1
Trilateral retinoblastoma: A systematic review of 211 cases.三侧性视网膜母细胞瘤:211例病例的系统综述
Neurosurg Rev. 2019 Mar;42(1):39-48. doi: 10.1007/s10143-017-0890-4. Epub 2017 Aug 16.
2
Trilateral retinoblastoma in transgenic mice.转基因小鼠中的三边视网膜母细胞瘤
Trans Am Ophthalmol Soc. 1989;87:301-22; discussion 322-6.

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