经导管动脉导管未闭封堵术后心肺功能状态的变化。
Changes in cardiorespiratory status after transcatheter patent ductus arteriosus closure.
作者信息
Coley Camryn, Sakaria Rishika, Philip Ranjit, Sathanandam Shyam, Weems Mark F
机构信息
University of Tennessee Health Science Center, Memphis, TN, USA.
Department of Pediatrics, Division of Neonatology, Le Bonheur Children's Hospital and the University of Tennessee Health Science Center, Memphis, TN, USA.
出版信息
J Perinatol. 2025 Jun 16. doi: 10.1038/s41372-025-02329-7.
OBJECTIVE
We aim to assess short-term cardiorespiratory outcomes of neonates after transcatheter patent ductus arteriosus (PDA) closure. We hypothesize pre-procedure respiratory severity score (RSS) ≥ 4 is associated with increased risk of post-transcatheter cardiorespiratory syndrome (PTCS).
STUDY DESIGN
This was a retrospective study of infants who underwent transcatheter PDA closure from January 2022 to December 2022. Patients were divided by pre-procedure RSS and analyzed for the development of PTCS or hypertensive cardiorespiratory failure.
RESULT
The study included 46 patients with a mean birthweight of 699 g and procedure weight of 1098 g. PTCS was identified in 5 (11%) patients with no differences based on pre-procedure RSS (8 vs 14%, p = 0.66). Post-procedure hypertension was found in 28 (61%) patients (58 vs 64%, p = 0.77), and occurred with respiratory failure in 12 (26%) patients (33 vs 18%, p = 0.32).
CONCLUSION
Pre-procedure RSS was not associated with post-procedure outcomes. While PTCS occurred infrequently, post-procedure hypertension was common.
目的
我们旨在评估经导管动脉导管未闭（PDA）封堵术后新生儿的短期心肺结局。我们假设术前呼吸严重程度评分（RSS）≥4与经导管心肺综合征（PTCS）风险增加相关。
研究设计
这是一项对2022年1月至2022年12月期间接受经导管PDA封堵术的婴儿进行的回顾性研究。患者根据术前RSS进行分组，并分析PTCS或高血压性心肺衰竭的发生情况。
结果
该研究纳入了46例患者，平均出生体重为699g，手术体重为1098g。5例（11%）患者被诊断为PTCS，根据术前RSS无差异（8%对14%，p = 0.66）。术后高血压在28例（61%）患者中发现（58%对64%，p = 0.77），12例（26%）患者发生呼吸衰竭（33%对18%，p = 0.32）。
结论
术前RSS与术后结局无关。虽然PTCS发生率较低，但术后高血压很常见。
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