Tongshuo Q U, Liping Zhang, Yuqing Zhao, Huan Zhang
Beijing University of Chinese Medicine, Beijing 100029, China.
Department of Gastrointestinal and Hepatobiliary, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing 100078, China.
J Tradit Chin Med. 2025 Jun;45(3):685-692. doi: 10.19852/j.cnki.jtcm.2025.03.003.
To explore the relationship between colorectal polyps and pulmonary nodules from the perspective of the lung and the large intestine being internally and externally connected, aiming to provide a theoretical basis for clinical diagnosis and treatment.
We retrospectively analyzed the data of patients who underwent electronic colonoscopy and were found to have colorectal polyps at the Gastrointestinal Endoscopy Center of Dongfang Hospital, Beijing University of Chinese Medicine, from January 1, 2017, to December 31, 2023. We also reviewed their lung CT results and used statistical software to analyze the recurrence, location, size, and pathology of colorectal polyps in relation to the presence, number, and size of pulmonary nodules.
Both colorectal polyps and pulmonary nodules are more common in elderly males. Patients with recurrent colorectal polyps are more likely to have pulmonary nodules, which tend to be located in the left colon and are more likely to be adenomatous in nature; those without pulmonary nodules show no clear pattern in polyp distribution, with a tendency towards inflammatory and hyperplastic pathology; the data from this study suggests that the proportion of lung nodules larger than 0.5 cm in the recurrent group is higher than in the non-recurrent group, and the proportion of colorectal polyps larger than 1 cm in the recurrent group is also higher than in the non-recurrent group.
There is a certain connection between the pathogenesis and treatment of colorectal polyps and pulmonary nodules. Cold, phlegm, dampness, blood stasis, and toxic coagulation are common pathogenic factors of the two diseases. Patients with larger colorectal polyps should be advised to undergo regular colonoscopy. Patients with recurrent polyps or those with left colon necrosis or cancer indicated by colonoscopy should be advised to complete lung related examinations to rule out the possibility of pulmonary nodules.
从肺与大肠相表里的角度探讨大肠息肉与肺结节之间的关系,旨在为临床诊疗提供理论依据。
回顾性分析2017年1月1日至2023年12月31日在北京中医药大学东方医院胃肠内镜中心接受电子结肠镜检查并发现大肠息肉的患者资料。同时查阅其肺部CT结果,运用统计软件分析大肠息肉的复发情况、部位、大小及病理类型与肺结节的存在、数量及大小之间的关系。
大肠息肉和肺结节在老年男性中更为常见。大肠息肉复发患者更易出现肺结节,且肺结节多位于左半结肠,性质上更倾向于腺瘤性;无肺结节患者的息肉分布无明显规律,病理类型多倾向于炎症性和增生性;本研究数据提示,复发组中直径大于0.5 cm的肺结节比例高于非复发组,复发组中直径大于1 cm的大肠息肉比例也高于非复发组。
大肠息肉与肺结节在发病机制及治疗方面存在一定联系。寒、痰、湿、瘀、毒结是这两种疾病的常见致病因素。对于大肠息肉较大的患者,应建议其定期进行结肠镜检查。对于息肉复发或结肠镜检查提示左半结肠有坏死或癌变的患者,应建议其完善肺部相关检查以排除肺结节的可能。