Khrapunov S N, Protas A F, Dragan A I, Berdyshev G D
Biofizika. 1985 Sep-Oct;30(5):791-6.
It has been found that histone octamer of calf thymus (H2A--H2B--H3--H4)2 can exist in two structural states--"loose" (2M NaCl) and "compact" one (4M NaCl). The compact state of the octamer is characterized by screening of part of tyrosyls for quenching effect of ions I-, longer relaxation time of tyrosyls, greater stability of histone H3 towards trypsinolysis, complete absence of interactions between histone H3 SH-groups and parachlormercuribenzoate.
已发现小牛胸腺组蛋白八聚体（H2A--H2B--H3--H4）2可存在于两种结构状态——“松散”状态（2M氯化钠）和“紧密”状态（4M氯化钠）。八聚体的紧密状态的特征在于部分酪氨酰基因I-离子的猝灭作用而被屏蔽、酪氨酰基的弛豫时间更长、组蛋白H3对胰蛋白酶消化的稳定性更高、组蛋白H3的巯基与对氯汞苯甲酸之间完全不存在相互作用。
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