Castillo Magaña Antonio, Gallardo-Navarro Elias, Gonzalez Aguirre Catalina, Salinas-García Grece Daniela
Head and Neck Surgery, Hospital Español, Mexico City, MEX.
General Surgery, Hospital Español, Mexico City, MEX.
Cureus. 2025 May 16;17(5):e84219. doi: 10.7759/cureus.84219. eCollection 2025 May.
Vagus nerve paragangliomas (PGL) are tumors derived from neural crest cells of very low incidence, and cervical PGL of the vagus nerves (VPGLs) are tumors, of which the nature and location make them extremely rare, representing only 0.012% of cervical tumors, with an incidence of 1:30,000-1:200,000. A 76-year-old woman presented with a rapid growth in volume in the left laterocervical region, accompanied by pain for four months. She denied voice changes, difficulty feeding, facial nerve paralysis, headache, hypertension, hearing loss, excessive sweating, tinnitus, and tremors. Catecholamines were requested in blood or urine, which were negative. A computed tomography angiography of the head and neck was performed, where a tumor was identified whose location and characteristics were diagnosed as a PGL of the left vagus nerve; no biopsy was performed. Head and neck surgeons should be aware of large vagal PGL involving nerve or vascular structures, as it is currently difficult to resect the tumor without sacrificing the vagus nerve, and postponing surgery may also increase patient morbidity.
迷走神经副神经节瘤(PGL)是起源于神经嵴细胞的肿瘤,发病率极低,而迷走神经的颈部PGL(VPGL)是一种肿瘤,其性质和位置使其极为罕见,仅占颈部肿瘤的0.012%,发病率为1:30000 - 1:200000。一名76岁女性,左颈外侧区域肿物体积迅速增大,并伴有四个月的疼痛。她否认有声音改变、进食困难、面神经麻痹、头痛、高血压、听力丧失、多汗、耳鸣及震颤。检测血或尿中的儿茶酚胺,结果为阴性。对头颈部进行了计算机断层血管造影,发现一个肿瘤,其位置和特征被诊断为左迷走神经的PGL;未进行活检。头颈外科医生应注意累及神经或血管结构的大型迷走神经PGL,因为目前在不牺牲迷走神经的情况下切除肿瘤很困难,而推迟手术也可能增加患者的发病率。