在一家城市性健康诊所实施多西环素暴露后预防措施后临床层面性传播感染负担的变化
Changes in clinic-level STI burden after doxycycline post-exposure prophylaxis implementation in an urban sexual health clinic.
作者信息
Jarolimova Jana, Bassett Ingrid V, Platt Laura, Germain Christine, Parker Robert A, Ard Kevin L
机构信息
Division of Infectious Disease, Massachusetts General Hospital, Boston, MA.
出版信息
Sex Transm Dis. 2025 Jun 17. doi: 10.1097/OLQ.0000000000002206.
Abstract
In an urban sexual health clinic, a substantial portion of the clinic population initiated doxycycline post-exposure prophylaxis (doxyPEP) for bacterial STIs in the first 12 months, and implementation of doxyPEP was associated with a subsequent decrease in clinic-level chlamydia and syphilis positivity, but no change in overall gonorrhea positivity.
摘要
在一家城市性健康诊所，很大一部分就诊者在最初12个月内开始使用多西环素进行暴露后预防（doxyPEP）以预防细菌性性传播感染，实施doxyPEP与随后诊所层面衣原体和梅毒阳性率的下降相关，但总体淋病阳性率没有变化。
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本文引用的文献
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Doxycycline Postexposure Prophylaxis and Bacterial Sexually Transmitted Infections Among Individuals Using HIV Preexposure Prophylaxis.在使用HIV暴露前预防药物的个体中，多西环素暴露后预防与细菌性性传播感染
JAMA Intern Med. 2025 Mar 1;185(3):273-281. doi: 10.1001/jamainternmed.2024.7186.
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Doxycycline Postexposure Prophylaxis and Sexually Transmitted Infection Trends.多西环素暴露后预防与性传播感染趋势
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Use of Doxycycline and Other Antibiotics as Bacterial Sexually Transmitted Infection Prophylaxis in a US Sample of Primarily Gay and Bisexual Men.在美国主要为男同性恋和双性恋男性的样本中，使用多西环素和其他抗生素作为细菌性性传播感染预防措施。
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