Glazer S, Vartanova M M, Konstantinova N N
Biull Eksp Biol Med. 1985 Oct;100(10):414-5.
Significant adverse correlation of the fetus mass and the degree of its hydration was noted at term in rats with placental insufficiency induced by ligation of about 40% of preplacental vessels on the 16th day of gestation. Disorders revealed in transplacental water-salt metabolism are apparently of some importance for the pathogenesis of fetal growth retardation. Even moderate retardation alters fetal respiratory activity in anoxia, which is associated with the changes in the function of respiratory centres and neuromuscular abnormalities.
在妊娠第16天结扎约40%胎盘前血管所致胎盘功能不全的大鼠足月时，观察到胎儿体重与其水合程度呈显著负相关。经胎盘水盐代谢紊乱显然对胎儿生长受限的发病机制具有一定重要性。即使是中度生长受限也会改变胎儿在缺氧时的呼吸活动，这与呼吸中枢功能变化及神经肌肉异常有关。
