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运用计算流体动力学分析主动脉夹层合并肠系膜灌注不良行主动脉开窗术失败的病例报告

Unsuccessful aortic fenestration for aortic dissection complicated with mesenteric malperfusion analyzed using computational fluid dynamics: a case report.

作者信息

Iwanaga Shoki, Kimura Naoyuki, Imada Shuta, Mizoguchi Mutsumi, Arakawa Mamoru, Akutsu Hirohiko, Kawahito Koji, Nakamura Masanori

机构信息

Department of Surgery, Division of Cardiovascular Surgery, Jichi Medical University, Yakushiji 3311-1, Shimotsuke, 329-0498, Japan.

Department of Electrical and Mechanical Engineering, Nagoya Institute of Technology, Gokiso, Showa, Nagoya, 466-8555, Japan.

出版信息

Gen Thorac Cardiovasc Surg Cases. 2025 Jun 17;4(1):28. doi: 10.1186/s44215-025-00212-7.

DOI:10.1186/s44215-025-00212-7
PMID:40528223
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12175397/
Abstract

BACKGROUND

We report a computational fluid dynamics (CFD)-based analysis of an unsuccessful open fenestration for aortic dissection with mesenteric malperfusion.

CASE PRESENTATION

A 75-year-old male was admitted for acute type B aortic dissection complicated by mesenteric malperfusion. He had a concomitant infrarenal abdominal aneurysm, prompting surgical infrarenal fenestration. Intraoperatively, the proximal intimal flap was resected near the renal arteries, and the aneurysm was replaced with a prosthetic graft. Despite the intervention, mesenteric malperfusion worsened, requiring additional endovascular aortic repair. CFD analysis revealed persistent false lumen flow and true lumen compression due to a large entry tear and residual proximal anastomotic stenosis.

CONCLUSION

CFD analysis suggests that a large entry tear and residual stenosis from insufficient fenestration may result in inadequate false lumen depressurization.

摘要

背景

我们报告了一项基于计算流体动力学(CFD)对肠系膜灌注不良的主动脉夹层开窗术失败的分析。

病例介绍

一名75岁男性因急性B型主动脉夹层合并肠系膜灌注不良入院。他同时患有肾下腹主动脉瘤,因此进行了手术肾下开窗术。术中,在肾动脉附近切除近端内膜瓣,并用人工血管置换动脉瘤。尽管进行了干预,但肠系膜灌注不良仍恶化,需要额外的血管腔内主动脉修复。CFD分析显示,由于大的入口撕裂和近端吻合口残余狭窄,假腔血流持续存在且真腔受压。

结论

CFD分析表明,大的入口撕裂和开窗不足导致的残余狭窄可能导致假腔减压不足。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9388/12175397/3f4e67f51610/44215_2025_212_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9388/12175397/72b4411caa93/44215_2025_212_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9388/12175397/a7719710c613/44215_2025_212_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9388/12175397/72605177f708/44215_2025_212_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9388/12175397/3f4e67f51610/44215_2025_212_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9388/12175397/72b4411caa93/44215_2025_212_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9388/12175397/a7719710c613/44215_2025_212_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9388/12175397/72605177f708/44215_2025_212_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9388/12175397/3f4e67f51610/44215_2025_212_Fig4_HTML.jpg

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本文引用的文献

1
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J Thorac Cardiovasc Surg. 2020 Nov;160(5):1151-1161.e1. doi: 10.1016/j.jtcvs.2019.09.065. Epub 2019 Sep 30.
2
Investigation of blood flow in the external carotid artery and its branches with a new 0D peripheral model.利用新型零维外周模型对外颈动脉及其分支的血流进行研究。
Biomed Eng Online. 2016 Feb 4;15:16. doi: 10.1186/s12938-016-0133-x.
3
Open fenestration for complicated acute aortic B dissection.复杂急性B型主动脉夹层的开窗手术
Ann Cardiothorac Surg. 2014 Jul;3(4):418-22. doi: 10.3978/j.issn.2225-319X.2014.07.08.
4
Type B aortic dissection after endovascular abdominal aortic aneurysm repair causing endograft collapse and severe malperfusion.血管腔内腹主动脉瘤修复术后发生B型主动脉夹层,导致腔内移植物塌陷和严重灌注不良。
J Vasc Surg. 2009 Aug;50(2):413-6. doi: 10.1016/j.jvs.2009.03.060.
5
Numerical simulation and experimental validation of blood flow in arteries with structured-tree outflow conditions.具有结构化树状流出条件的动脉血流数值模拟与实验验证。
Ann Biomed Eng. 2000 Nov-Dec;28(11):1281-99. doi: 10.1114/1.1326031.
6
Structured tree outflow condition for blood flow in larger systemic arteries.较大体循环动脉中血流的结构化树状流出条件。
Am J Physiol. 1999 Jan;276(1):H257-68. doi: 10.1152/ajpheart.1999.276.1.H257.