Torres J, Volpato R D, Power E G, Lopez E C, Dominguez M E, Maira J L, Ugarte J A, Martinez V C
Cancer. 1985 Nov 1;56(9):2298-304. doi: 10.1002/1097-0142(19851101)56:9<2298::aid-cncr2820560927>3.0.co;2-l.
One hundred forty-eight patients with differentiated carcinoma of the thyroid treated between May 1954 and April 1973 are presented. There were 89 papillary and 59 follicular carcinomas. They were classified according to Woolner criteria. Treatment consisted of surgery I-131 and thyroid hormone. Recurrences occurred in 8.7% of the patients, and lethality at the end of the observation period was 3.3%. The impact of histologic type, extent of the primary, and age of the patient at the time of treatment on prognosis were studied. The data were submitted to statistical analysis. This study revealed that these factors are determinant on prognosis. Best survival rates were observed in patients 40 years of age or younger at the time of treatment, in patients with intrathyroid papillary carcinomas, and in patients with noninvasive follicular carcinomas.
本文报告了1954年5月至1973年4月期间接受治疗的148例甲状腺分化癌患者。其中有89例乳头状癌和59例滤泡状癌。它们根据伍尔纳标准进行分类。治疗包括手术、碘-131和甲状腺激素。8.7%的患者出现复发,观察期末的死亡率为3.3%。研究了组织学类型、原发灶范围和治疗时患者年龄对预后的影响。数据进行了统计分析。该研究表明这些因素对预后具有决定性作用。治疗时年龄在40岁及以下的患者、甲状腺内乳头状癌患者以及非侵袭性滤泡状癌患者的生存率最佳。