Singh Amandeep, Arora Manik, Awal Guneet, Sood Mehar Kaur
Department of Radiodiagnosis & Imaging, Sri Guru Ram Das Institute of Medical Sciences and Research, Amritsar, Punjab, India.
Sri Guru Ram Das Institute of Medical Sciences and Research, Amritsar, Punjab, India.
Indian J Radiol Imaging. 2025 Jan 30;35(3):424-430. doi: 10.1055/s-0044-1801761. eCollection 2025 Jul.
Diabetes mellitus (DM) leads to diabetic peripheral neuropathy (DPN), a significant complication affecting a large percentage of diabetic patients. Traditional methods like nerve conduction studies have limitations in diagnosing DPN, especially in advanced cases. High-resolution ultrasound has emerged as a valuable tool in enhancing diagnostic accuracy. The aim of the study is to evaluate the efficacy of shear wave elastography (SWE) in assessing DPN, focusing on the tibial and median nerves. The study involved 100 participants categorized into groups with DPN, DM without DPN, and healthy controls. SWE was performed on the tibial and median nerves, and statistical analysis was conducted to compare the findings among the groups. The study found significant increases in SWE values from the normal group to the DM group, and further increases in the DPN group for both tibial and median nerves. Receiver operating characteristic analysis indicated high diagnostic accuracy of SWE in distinguishing DPN from non-DPN cases. Overall, the study suggests that SWE could be a valuable adjunctive imaging tool in diagnosing DPN, offering advantages in terms of sensitivity, specificity, and noninvasiveness. The study concludes that SWE of the tibial and median nerves is a noninvasive, sensitive, and specific method for detecting DPN. Combining high-resolution ultrasound with SWE enhances the diagnostic accuracy of DPN.
糖尿病（DM）会导致糖尿病性周围神经病变（DPN），这是一种影响很大比例糖尿病患者的严重并发症。像神经传导研究这样的传统方法在诊断DPN方面存在局限性，尤其是在晚期病例中。高分辨率超声已成为提高诊断准确性的一种有价值的工具。 本研究的目的是评估剪切波弹性成像（SWE）在评估DPN方面的有效性，重点关注胫神经和正中神经。 该研究纳入了100名参与者，分为DPN组、无DPN的DM组和健康对照组。对胫神经和正中神经进行了SWE检查，并进行了统计分析以比较各组的结果。 研究发现，从正常组到DM组，SWE值显著增加，而DPN组的胫神经和正中神经的SWE值进一步增加。受试者工作特征分析表明，SWE在区分DPN与非DPN病例方面具有较高的诊断准确性。总体而言，该研究表明SWE可能是诊断DPN的一种有价值的辅助成像工具，在敏感性、特异性和非侵入性方面具有优势。 该研究得出结论，胫神经和正中神经的SWE是检测DPN的一种非侵入性、敏感且特异的方法。将高分辨率超声与SWE相结合可提高DPN的诊断准确性。
